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rosuvastatin

   Also found in: Wikipedia 0.01 sec.
rosuvastatin,
an antilipemic.
indications This drug is used as an adjunct in primary hypercholesterolemia (types IIa and b), mixed dyslipidemia, elevated serum triglycerides, and homozygous low-density lipoprotein receptor disorder.
contraindications Pregnancy, lactation, active liver disease, and known hypersensitivity to this drug prohibit its use.
adverse effects Adverse effects of this drug include vomiting; leg, shoulder, or localized pain; insomnia; paresthesia; photosensitivity; rhinitis; sinusitis; bronchitis; and increased cough. Life-threatening side effects include liver dysfunction, myositis, rhabdomyolysis, thrombocytopenia, hemolytic anemia, and leukopenia. Common side effects include nausea, constipation, abdominal pain, flatus, diarrhea, dyspepsia, heartburn, asthenia, muscle cramps, arthritis, arthralgia, myalgia, headache, dizziness, rash, pruritus, and pharyngitis.


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Gulhati said the drug rosuvastatin, a cholesterol lowering drug, has different action on North Americans, Europeans and Indians.
In the ASTEROID Trial, 346 participants completed a two-year course of treatment with the cholesterol drug, rosuvastatin (Crestor[R]), 40 mg (the maximum FDA-approved dose).
The study dubbed Jupiter -- Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin -- found that taking the British lab AstraZeneca's Crestor reduced the clot risk in the veins by as much as 40 percent and more.
 
 
 
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