rosiglitazone


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Related to rosiglitazone: metformin, thiazolidinedione, troglitazone

rosiglitazone

 [ro-sig-lit´ah-zōn]
an antidiabetic agent that increases insulin sensitivity, used orally as the maleate salt in the treatment of type 2 diabetes mellitus.

rosiglitazone

/ro·sig·lit·a·zone/ (ro-sig-lit´ah-zōn) an antidiabetic agent that increases insulin sensitivity, used as the maleate salt in the treatment of type 2 diabetes mellitus.

rosiglitazone

(rō′sĭ-glĭt′ə-zōn′)
n.
A thiazolidinedione drug, C18H19N3O3S, used in its maleate form to treat type 2 diabetes.

rosiglitazone

an oral antidiabetic.
indication It is used to treat stable type 2 diabetes mellitus.
contraindications Lactation, diabetic ketoacidosis, and known hypersensitivity to thiazolidinediones prohibit its use. It is also contraindicated in children.
adverse effects Adverse effects include upper respiratory infection, sinusitis, anemia, back pain, diarrhea, edema, fatigue, headache, and hyperglycemia or hypoglycemia.

rosiglitazone

Avandia® Therapeutics A thiazolidinedione used in Pts with type 2 DM to ↑ the efficiency with which the body uses insulin Adverse effects Flu-like Sx, headache, weight gain Contraindications CHF

rosiglitazone

A THIAZOLIDINEDIONE drug used to control HYPERGLYCAEMIA in patients with Type 2 DIABETES. It reduces insulin resistance and has been found capable of restoring normoglycaemia and reducing the incidence of Type 2 diabetes in patients with impaired glucose rolerance or impaired fasting glucose levels, or both.
References in periodicals archive ?
Intervention: 5,565 patients assigned to regimens including rosiglitazone (doses ranging from 2 mg-8 mg).
In a manner similar to the publication in JAMA of an analysis of the cardiovascular safety of muraglitizar, the analysis of rosiglitazone was published as an "emergency paper" because of the purported effect size and the potential consequences of this impacting millions of lives around the world.
He suggested that meta-analyses might be less revealing than the results of individual trials, and pointed to three such trials: ADOPT (A Diabetes Outcome Progression Trial) and DREAM (Diabetes Reduction Assessment with Ramipril and Rosiglitazone Medication), both of which have been completed; and RECORD (Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycaemia in Diabetes), which is ongoing.
Women were randomized to metformin or rosiglitazone monotherapy for 12 weeks, followed by 12 weeks of combination therapy.
A total of 208 children aged 8-17 years with type 2 diabetes entered a 4-week run-in period, and 200 were randomized to either rosiglitazone 2 mg twice daily or metformin 500 mg twice daily.
Rosiglitazone in the treatment of HAART-associated lipodystrophy (HAL): A randomized, double-blind, placebo-controlled trial.
If you take pioglitazone or rosiglitazone, it is important for your health care provider to check your liver enzyme levels regularly.
In differentiating rosiglitazone from other agents, Harold E.
Concurring with the recommendations of two expert advisory panels in June, the FDA is modifying the cardiovascular safety statement in the labels of rosiglitazone products, changing the rosiglitazone Risk Evaluation and Mitigation Strategy (REMS), and releasing the manufacturer from a requirement to conduct a postmarketing safety stud); according to the announcement.
Washington, June 9 ( ANI ): A re-analysis of the data from a pivotal study of rosiglitazone found no increased risk of cardiovascular events associated with the controversial diabetes drug.
Rosiglitazone containing products are now indicated only in patients with Type 2 diabetes mellitus for whom all other oral ant diabetic agents in monotherapy or in combination do not result in adequate glycemic control.