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rofecoxib

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rofecoxib /ro·fe·cox·ib/ (ro″fĕ-cok´sib) a nonsteroidal anti-inflammatory drug used in the treatment of osteoarthritis, acute pain, and dysmenorrhea.
ro·fe·cox·ib (rf-kksb)
n.
A nonsteroidal anti-inflammatory drug that selectively inhibits the formation of prostaglandins and was formerly used to treat pain, especially in osteoarthritis.

rofecoxib [ro″fĕ-cok´sib]
a nonsteroidal antiinflammatory drug of the cox-2 inhibitors group, used in treatment of osteoarthritis, acute pain, and dysmenorrhea.

rofecoxib
Vioxx® Pain management An analgesic Cox-2 inhibitor. See Cox-2 inhibitor, Cyclooxygenase.


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Byline: ANI Washington, Nov 24 (ANI): A new American report suggests that clinical trial data had pointed out the association between the anti-inflammatory drug rofecoxib and cardiovascular risk nearly eight years ago.
The most well-known recent example of drug withdrawal due to toxicity is the selective COX-2 inhibitor, rofecoxib (Vioxx), which increased the risk of cardiovascular disease.
COX-2 inhibitor drugs, particularly rofecoxib (Vioxx), have gone through a public flogging because of reported elevated incidences of cardiovascular events (heart attacks and strokes) in patients taking them for arthritis.
 
 
 
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