translocation /trans·lo·ca·tion/ (trans″lo-ka´shun) the attachment of a fragment of one chromosome to a nonhomologous chromosome. Abbreviated t.
robertsonian translocation
reciprocal translocation the complete exchange of fragments between two broken nonhomologous chromosomes, one part of one uniting with part of the other, with no fragments left over. Abbreviated rcp.
robertsonian translocation translocation involving two acrocentric chromosomes, which fuse at the centromere region and lose their short arms.
rob·ert·son·i·an translocation (r b  rt-s  n -n)n. A breakage in the short arms of two acrocentric chromosomes and the subsequent fusion of the long arms into a single chromosome. Also called centric fusion. |
robertsonian translocation
[rob′ərtsō′nē·ən]
the exchange of entire chromosome arms, with the break occurring at the centromere, usually between two nonhomologous acrocentric chromosomes. It produces one large, metacentric chromosome and one extremely small chromosome. The latter carries little genetic material and may be lost through successive cell divisions, leading to a reduction in total chromosome number. Compare balanced translocation, reciprocal translocation.
Robertsonian translocation
see Robertsonian translocation.
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