rizatriptan


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Related to rizatriptan: sumatriptan, Rizatriptan benzoate

rizatriptan

 [ri″zah-trip´tan]
a selective serotonin receptor agonist used as the benzoate salt in the acute treatment of migraine.

rizatriptan

/ri·za·trip·tan/ (ri″zah-trip´tan) a selective serotonin receptor agonist used as the benzoate salt in the acute treatment of migraine.

rizatriptan

(rĭz′ə-trĭp′tn)
n.
An oral drug of the triptan class, C15H19N5, used in its benzoate form to treat migraine headaches.

rizatriptan

a migraine agent.
indication It is used in the acute treatment of migraine.
contraindications Factors prohibiting its use include angina pectoris, a history of myocardial infarction, documented silent ischemia, Prinzmetal's angina, ischemic heart disease, concurrent use of ergotamine-containing preparations, uncontrolled hypertension, basilar or hemiplegic migraine, and known hypersensitivity.
adverse effects Adverse effects include chest tightness, chest pressure, nausea, and dry mouth. Common side effects include dizziness, headache, and fatigue.
References in periodicals archive ?
Rogers, Disposition and Pharmacokinetics of the Antimigraine Drug, Rizatriptan, in Humans, Drug.
5 mg Cardiac disease, Rizatriptan 10 mg uncontrolled HTN, Sumatriptan 50 mg, 100 mg concomitant ergotamine/ Zolmitriptan 1.
5 mg oral Randomized controlled trial [37] Rizatriptan 10 mg oral Randomized controlled trial [38], motion sickness Prophylactic medications Propranolol 160 mg, 40-160 mg Retrospective cohort analysis [39-41] Propranolol/ 40~160 mg/37.
Sometimes they were told it was an effective migraine drug named rizatriptan, a positive message.
This therapeutic class comprises seven members, namely, sumatriptan, zolmitriptan, rizatriptan, eletriptan, almotriptan, naratriptan, and the latest one "frovatriptan.
Prior to evaluation and treatment at the headache clinic, she had tried multiple regimens including, over-the-counter medications, combination acetaminophen, butalbital, and caffeine, oral contraceptive pills, amitriptyline, propranolol, verapamil, gabapentin, sumpatriptan, frovatriptan, rizatriptan and eletriptan, without significant relief.
Specific triptans include naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex), zolmitriptan (Zomig), almotriptan (Axert), frovatriptan (Frova) and eletriptan (Relpax).
Nasal sumatriptan 10 mg (20 - 39 kg) and 20 mg (>39 kg) has been shown to be effective in an 8 - 17-year age group, as was rizatriptan 5 mg (20 - 39 kg) and 10 mg (>39 kg) in this age group.
BERLIN -- Rizatriptan fought migraine more effectively in children and adolescents when it was dosed according to body weight in a randomized, double-blind parallel group trial.
Thus, several potent drugs possessing triazole nucleus have been applied in medicine, like, Alprazolam (anxiolytic agent and tranquilizer), Anastrozole, Letrozole, Vorozole (antineoplastics and nonsteroidal competitive aromatase inhibitors), Estazolam (hypnotic, sedative and tranquilizer), Etoperidone (antidepressant), Fluconazole, Itraconazole, Terconazole (antifungal agents), Ribavirin (antiviral agent), Benatradin (diuretic), Rilmazafon (hypnotic, anxiolytic and used in the case of neurotic insomnia), Nefazodone (antidepressant and 5-HT2 A-antagonist), Rizatriptan (antimigraine agent), Trapidil (hypotensive), Trazodone (antidepressant, anxiolytic and selectively inhibits central serotonin uptake) and Triazolam (sedative and hypnotic) [18].
John's wort), imipramine, MDMA, meperidine, nefazodone, nortriptyline, paroxetine, protriptyline, sertraline, tramadol, trazodone, venlafaxine Drugs that decrease Isocarboxazid, linezolid, phenelzine, 5-HT metabolism selegiline, tranylcypromine Drugs that are direct Almotriptan, buspirone, dihydroergotamine, 5-HT agonists eletriptan, frovatriptan, LSD, naratriptan, rizatriptan, sumatriptan, zolmitriptan Others L-tryptophan, carbamazepine, carisoprodol, droperidol, levodopa, lithium, metoclopramide, pentazocine, phenylpropanolamine 5-HT: serotonin; LSD: lysergic acid; MDMA: methylenedioxymethamphetamine Source: Reference 1