cofactor

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Related to ristocetin cofactor: mixing study

cofactor

 [ko´fak-ter]
an element or principle, e.g., a coenzyme, with which another must unite in order to function.
heparin cofactor II a member of the serpin group that inhibits thrombin.

co·fac·tor

(kō'fak'ter, tōr),
1. Synonym(s): coenzyme
2. An atom or molecule essential for the action of a large molecule, for example, heme in hemoglobin, magnesium in chlorophyll. Solo metal ions are regarded as cofactors for proteins, but not as coenzymes.

cofactor

/co·fac·tor/ (ko´fak-ter) an element or principle, e.g., a coenzyme, with which another must unite in order to function.
heparin cofactor II  a serine proteinase inhibitor of the serpin family that inhibits thrombin.

cofactor

(kō′făk′tər)
n.
1. One of two or more contributing factors.
2. A substance, such as a metallic ion or coenzyme, that must be associated with an enzyme for the enzyme to function.

co·fac·tor

(kō'fak'tŏr)
1. Synonym(s): coenzyme.
2. An atom or molecule essential for the action of a large molecule; e.g., heme in hemoglobin, magnesium in chlorophyll.

cofactor

a substance that is essential for the catalytic activity of some enzymes, binding to the enzyme only during the reaction. Cofactors can be metallic ions, or nonprotein organic molecules (coenzymes) such as vitamins in the B-COMPLEX.

co·fac·tor

(kō'fak'tŏr)
An atom or molecule essential for the action of a large molecule.

cofactor

an element or principle, e.g. a coenzyme, with which another must unite in order to function.

ristocetin cofactor
see ristocetin cofactor.
References in periodicals archive ?
Differential sensitivity of von Willebrand factor (VWF) 'activity' assays to large and small VWF molecular weight forms: a cross-laboratory study comparing ristocetin cofactor, collagen-binding and mAb-based assays.
4] Nonstandard abbreviations: vWF, von Willebrand factor; vWD, von Wille brand disease; DDAVP, 1-deamino-[8-D-arginine]-vasopressin; vWF:Ag, vWF antigen; vWF:RCof, ristocetin cofactor activity; vWF:CB, collagen-binding assay; FCS, fluorescence correlation spectroscopy; TRITC, tetramethyl-rhodamine isothiocyanate.
The analytical variability of existing Ristocetin Cofactor test systems is high -- 30%, and inter laboratory variability is about the same.
Von Willebrand factor collagen binding activity in diagnosis of von Willebrand disease: an alternative to ristocetin cofactor activity?
Ristocetin cofactor activity by BCS analyzer [Package Insert].
The ristocetin cofactor is a test to assess VWF activity.
Bick added, "During the quarter, we received FDA approval for two new products: one for use in the immunological detection of von Willebrand's factor, which complements our Ristocetin Cofactor Assay, both used in the detection and diagnosis of von Willebrand disease; the second for a new multi-analyte Drugs-of-Abuse Control, which was the result of a joint development effort with Biosite Diagnostics, Inc.
Bio/Data Corporation ("Bio/Data") announced it has added a normal control plasma to its ristocetin cofactor assay product line, the family of reagents used in conjunction with the company's Platelet Aggregation Profiler(R) to estimate the quantity of von Willebrand Factor ("vWF") in plasma samples.
Confirmation of vWD diagnosis can be achieved with laboratory tests which measure von Willebrand factor activity such as vWF antigen and ristocetin cofactor assay.