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ristocetin
(redirected from ristocetin cofactor)

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.01 sec.
ristocetin
an antibiotic produced by cultures of the actinomycete Nocardia lurida. Used also in the assessment of platelet function.

ristocetin cofactor
inolved in platelet aggregation. Called also von Willebrand factor.


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11) Test for von Willebrand disease For more than two decades, the ristocetin cofactor (RCo) assay, which measures the vWF-mediated agglutination of platelets in the presence of the antibiotic ristocetin, has been the most common method for measuring the functional activity of vWF.
The company also developed the first automated ristocetin cofactor activity test that detects Von Willebrand disease, which is the most common inherited bleeding disorder.
These variants are differentiated on the basis of a panel of lab tests that include the bleeding time, platelet count, partial thromboplastin time, yon Willebrand factor (vWF) activity and antigen, factor VIII levels, ristocetin cofactor, and vWF multimeric composition.
 
 
 
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