Nigel Brooksby, managing director of sanofi-aventis UK, which makes the drug, said: "We are delighted Nice has recognised the role rimonabant
can play in helping health-care professionals manage obese and overweight patients.
Early indications for a drug in development for weight loss, rimonabant
(Zimulti), show possible efficacy blocking the "high" of smoked cannabis as well, Dr.
The Food and Drug Administration's advisory panel turned down the drug, also known as rimonabant
and Ziumlti, after hearing testimony that it increases the risk of suicidal thoughts, even in patients without a history of depression.
The outstanding weight loss and cardiovascular-risk reduction previously reported after 1 year of rimonabant
therapy were maintained after 2 years of treatment in the phase III Rimonabant
in Obesity-Europe trial, Luc Van Gaal, M.
Weight loss Obese adults taking a diet drug called rimonabant
lost weight and kept it off, with continued dieting, for at least 2 years (166: 325 *).
Researchers hailed the latest results from trials of the rimonabant
pill, which targets the part of the brain involved in motivation and controlling appetite.
He said of the Rimonabant
trials: "We are excited for several reasons.
Two reports on the drug, called rimonabant
, were reviewed at the recent meeting of the American College of Cardiology.
The review authors examined research regarding three weight-loss drugs - orlistat, sibutramine and rimonabant
Previously identified ingredients include sibutramine, the active ingredient in the FDA-approved obesity drug Meridia; the anti-epileptic drug phenytoin; and rimonabant
, an obesity drug that was denied approval in the United States because of neurologic and psychiatric side effects.
There's much good about rimonabant
," said obesity expert Dr.
targets a natural body system that governs factors controlling appetite, weight, metabolism and energy use.