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rifamycin

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rifamycin /rif·a·my·cin/ (rif″ah-mi´sin) any of a family of antibiotics biosynthesized by a strain of Streptomyces mediterranei, effective against a broad spectrum of bacteria, including gram-positive cocci, some gram-negative bacilli, and Mycobacterium tuberculosis and certain other mycobacteria; used for the treatment of tuberculosis and the prophylaxis of meningococcal infections.
rif·a·my·cin (rf-msn)
n.
Any of a group of antibiotics originally isolated from a strain of the soil microorganism Streptomyces mediterranei, used in the treatment of leprosy, tuberculosis, and other bacterial diseases.

rifamycin
[rif′ah-mi′sin]
any of a family of antibiotics biosynthesized from a strain of Streptomyces mediterranei, effective against a broad spectrum of bacteria. The five components are designated A, B, C, D, and E; rifamycins O, S, and SV are derivatives of the B component, and AG and X are derivatives of the O component. It is used for the initial treatment and retreatment of pulmonary tuberculosis and for prevention of meningococcal infections in close contacts of patients with Neisseria meningitidis infections.

rifamycin [rif″ah-mi´sin]
any of a family of antibiotics biosynthesized by a strain of Streptomyces mediterranei, effective against a broad spectrum of bacteria. The five components are designated A, B, C, D, and E; rifamycins O, S, and SV are derivatives of the B component, and AG and X are derivatives of the O component. Used for the initial treatment and retreatment of pulmonary tuberculosis and for prevention of meningoccal infections in close contacts of patients with Neisseria meningitidis infections.

rifamycin
a family of antibiotics produced in cultures of Streptomyces mediterranei. Effective against gram-positive cocci and gram-negative bacilli and mycobacteria including Mycobacterium tuberculosis.


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25 Hardcover RM666 Rifaximin, a semisynthetic rifamycin which is nonabsorbable in the gastrointestinal tract, has been available in Europe and other countries for several years and has recently been approved in the US for treatment of traveler's diarrhea.
One recent report of clofazimine combined with a macrolide and ethambutol without the use of any rifamycin showed successful treatment with an 87% sputum conversion rate after 10 months of therapy.
 
 
 
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