The past decade saw an increase in tick-borne rickettsial diseases
across the U.
Nevertheless, insect localization and removal as soon as possible, preferably within 36 hours, remain recommended strategies to prevent ixodid tickborne rickettsial diseases
Jill Hacker, PhD, Sharon Messenger, PhD, Debra Wadford, PhD, Dongxiang Xia, PhD, Viral and Rickettsial Disease
Laboratory, California Department of Public Health.
There may be several reasons for this favorable outcome, including a large percentage of benign African tick bite fever cases, and a widespread empiric use of antirickettsial drugs in cases of suspected rickettsial disease
Reported by: A Deckert, MD, Shasta County Public Health, Redding; C Glaser, MD, Viral and Rickettsial Disease
Laboratory: B Sun, DVM, Div of Communicable Disease Control, California Dept of Health Svcs.
C Hanlon, VMD, L Orciari, MS, M Niezgoda, MS, J Smith, MS, Div of Viral and Rickettsial Diseases
, National Center for Infectious Diseases, CDC.
Ms Jean is the coordinator of the California West Nile virus human surveillance program in the California Department of Public Health Viral and Rickettsial Disease
The presence of 3 rickettsial diseases
on this small island demonstrates the complexity of rickettsial epidemiology in Australia.
At this time the possibility of rickettsial disease
was raised, and appropriate tests were performed.
Microimmunofluorescence (MIF) assay is the test of choice to diagnose rickettsial diseases
(1,2), but more sensitive serologic tests and real-time quantitative PCR are expected to increase the number of cases diagnosed (3).
Subsequent damage to the endothelium is followed by endothelial-cell activation and perivascular infiltration of lymphocytes, macrophages, and polymorphonuclear leukocytes, resulting in inflammatory vasculitis of dermal vessels, the histopathologic hallmark of rickettsial disease
, and possibly thrombosis (23).
felis in WA; consequently, this rickettsial disease
should be included as a differential diagnosis for influenzalike illnesses in persons who own or work with companion animals.