ricin

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Related to ricin toxin: anthrax, Anthrax toxin, Botulism toxin

ricin

 [ri´sin]
a phytotoxin in the seeds of the castor oil plant (Ricinus communis), inhalation or ingestion of which causes intoxication, producing superficial inflammation of the respiratory mucosa with hemorrhages into the lungs, or edema of the gastrointestinal tract with hemorrhages.

ri·cin

(rī'sin, ris'in),
A highly toxic lectin and hemagglutin that occurs in castor beans (the seeds of the castor oil plant, Ricinus communis; if ingested, acts as a violent irritant with possibly fatal results, on the respiratory and gastrointestinal mucosa; an N-glycosidase that acts on the GOS subunit of rRNA, halting protein translation.

ricin

/ri·cin/ (ri´sin) a phytotoxin in the seeds of the castor oil plant (Ricinus communis), used in the synthesis of immunotoxins.

ricin

[rī′sin]
a poison made from waste produced in processing castor beans. It can take the form of a powder, mist, or pellet or can be dissolved in water or weak acid and can be used as a poison by ingestion, inhalation, or injection. As little as 500 micrograms can be a fatal dose. It cannot be spread by person-to-person contact. Poisoning is treated by minimizing exposure and by supportive care. There is no antidote. Also called ricinine. See also ribosome-inactivating protein.

ricin

Toxicology A toxic vegetable poison from the castor bean plant–Ricinus communis which causes agglutination and fulminant hemolysis at very high dilutions–1/106 Clinical Abdominal pain, nausea, cramps, convulsions, dehydration, hemolysis, cyanosis, renal failure–oliguria, hematuria, circulatory collapse. See Magic bullet.

ri·cin

(rī'sin)
Toxin derived from castor beans that causes inflammation of the gastrointestinal mucosa and the respiratory tract.
[L. ricinus, castor oil plant]

ricin

A highly poisonous substance found in the castor oil bean Ricinis communis .

ri·cin

(rī'sin)
A highly toxic lectin and hemagglutinin that occurs in castor beans (the seeds of the castor oil plant, Ricinus communis); if ingested, acts as a violent irritant with possibly fatal results, on the respiratory and gastrointestinal mucosa.
[L. ricinus, castor oil plant]

ricin

phytotoxin (combining lectin, toxalbumin, hemagglutinin) in the seeds of the castor oil plant (Ricinus communis), inhalation or ingestion of which causes intoxication, producing superficial inflammation of the respiratory mucosa with hemorrhages into the lungs, or edema of the gastrointestinal tract with hemorrhages.
References in periodicals archive ?
The successful development of an effective vaccine against ricin toxin may act as a deterrent against the actual use of ricin as a biological weapon and could be used in rapid deployment scenarios in the event of a biological attack.
About RiVax(TM) RiVax(TM) is our proprietary vaccine candidate being developed to protect against exposure to ricin toxin, and if approved would be the first ricin vaccine.
The enzymatic ricin toxin A subunit (RTA) is an RNA-N-glycosidase which cleaves a specific adenine residue with eukaryotic 28S ribosomal RNA, leading to protein synthesis arrest and cell death.
Ricin toxin is a potential bioterror threat that is toxic in small doses, is easy to obtain, and has the ability to be aerosolized.
Soligenix has been developing RiVax(TM), its proprietary ricin toxin vaccine, in conjunction with its heat stabilization technology, ThermoVax(TM), as a heat-stable biodefense vaccine.
OTCBB:DORB) ("DOR" or the "Company"), announced today that it has successfully completed its cGMP (current Good Manufacturing Practices) milestone for the production of RiVax(TM), DOR's vaccine against ricin toxin.
OTCQB: SNGX) (Soligenix or the Company), a late-stage biopharmaceutical company developing products that address unmet medical needs in the areas of inflammation, oncology and biodefense, announced today the publication of data demonstrating that the combination of RiVax(TM) and VeloThrax(TM) induces protective immunity to both ricin toxin and anthrax toxin exposure.
The objectives of the contract are to advance the development of Soligenix's thermostabilization technology, ThermoVax(TM), combined with the company's ricin toxin vaccine, Rivax(TM), as a medical countermeasure to prevent the effects of ricin exposure.
In January 2006, AVI gained approval for an $11 million allocation as part of the Defense Appropriations Act to develop therapeutic agents against Ebola, Marburg and dengue viruses, as well as countermeasures for anthrax exposure and antidotes for ricin toxin.
E[acute accent]Using the company's dual stage filter architecture, Nephros has developed a new proprietary water filtration device that is designed to remove a broad range of bacteria, viral agents and toxic substances, including salmonella, hepatitis, HIV, Ebola virus, ricin toxin, legionella, fungi and e-coli.
All vaccinated animals exposed to a lethal aerosol of ricin toxin survive
OTCQB: SNGX) (Soligenix or the Company), a clinical stage biopharmaceutical company focused on developing products to treat serious inflammatory diseases where there remains an unmet medical need, as well as developing several biodefense vaccines and therapeutics, announced today that the combination of RiVax(TM) and VeloThrax(TM) induces protective immunity to both ricin toxin and anthrax toxin exposure.