Recent advances have highlighted few strain-specific parasite effectors released from the rhoptry
into the host cells where they neutralize cell autonomous immunity defences or subvert the host cell transcriptome thereby governing the fate of immune response and disease outcomes.
Some studies showed usefulness of rhoptry protein 1 (ROP1) antigen of Toxoplasma gondii (T goncli0 in serodiagnosis of the infection and induction of protective immunity.
Rhoptry proteins have key biological roles in penetration into the host cell, and may facilitate the formation of the Parasitophorous Vacuole (PV) and mediate its clustering with host cell organelles (15).
Rhoptry organelles of the api-complexa: their role in host cell invasion and intracellular survival.
Characterization of TgROP9 (p36), a novel rhoptry protein of Toxoplasma gondii tachyzoites identified by T cell clone.
17) On the other hand, DNA vaccine of plasmid encoding the rhoptry protein 1 gene combined with the genetic adjuvant of pcIFN-[gamma], applied against T.
Immunity induced by DNA vaccine of plasmid encoding the rhoptry protein 1 gene combined with the genetic adjuvant of pcIFN-gamma against Toxoplasma gondii in mice.
Protective immunity induced by Toxoplasma gondii rhoptry protein 16 against toxoplasmosis in mice.
Characterisation of a family of multicopy genes encoding rhoptry
protein homologues in Babesia bovis, Babesia ovis and Babesia canis.
Juridical Foundation The Chemo-Sero-Therapeutic Research Institute (Kumamoto-shi, Japan) has patented a gene encoding a protein from merozoite of Babesia caballi, a recombinant protein of Babesia caballi, and an antibody capable specifically binding to a 48 kDa protein of rhoptry
of Babesia caballi merozoite.
TgSUB1 is a microneme protein, whereas TgSUB2 localizes to rhoptries and associates with rhoptry
protein ROP1, a potential substrate.
Plasmodium falciparum uses several proteins, including the 155-kDa ring-infected surface antigen and the 140/130/1l0/-kDa rhoptry
complex, to bind to appropriate erythrocyte membranes (Sam-Yellowe, 1992).