rhabdomyosarcoma


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rhabdomyosarcoma

 [rab″do-mi″o-sahr-ko´mah]
a highly malignant tumor arising in striated muscle or in embryonal mesenchymal cells that exhibit differentiation along rhabdomyoblastic lines, including but not limited to the presence of cells with recognizable cross striations. The pleomorphic form affects predominantly the skeletal muscles of adults; the embryonal-alveolar form occurs mainly in the skeletal muscles of children and young adults, and the embryonal-botryoid form occurs predominantly in tissues of the head, neck, orbit, and urogenital tract of children and young adults.

rhab·do·my·o·sar·co·ma

(rab'dō-mī'ō-sar-kō'mă),
A malignant neoplasm derived from skeletal (striated) muscle, occurring in children or, less commonly, in adults; classified as embryonal alveolar (composed of loose aggregates of small round cells) or pleomorphic (containing rhabdomyoblasts).
Synonym(s): rhabdosarcoma
[rhabdo- + G. mys, muscle, + sarkōma, sarcoma]

rhabdomyosarcoma

/rhab·do·myo·sar·co·ma/ (mi″o-sahr-ko´mah) a highly malignant tumor of striated muscle derived from primitive mesenchymal cells.
alveolar rhabdomyosarcoma  a type having dense proliferations of small round cells among fibrous septa that form alveoli, seen mainly in adolescents and young adults.
embryonal rhabdomyosarcoma  a type having alternating loosely cellular areas with myxoid stroma and densely cellular areas with spindle cells, seen mainly in infants and small children.
pleomorphic rhabdomyosarcoma  a type having large cells with bizarre hyperchromatic nuclei, seen in the skeletal muscles, usually in the limbs of adults.

rhabdomyosarcoma

[rab′dōmī′ō·särkō′mə] pl. rhabdomyosarcomas, rhabdomyosarcomata
Etymology: Gk, rhabdos + mys, muscle, sarx, flesh, oma
a highly malignant tumor derived from primitive striated muscle cells that occurs most frequently in the head and neck and is also found in the genitourinary tract, extremities, body wall, and retroperitoneum. In some cases the onset is associated with trauma. The initial symptoms depend on the site of tumor development and indicate local tissue or organ destruction, such as dysphagia, vaginal bleeding, hematuria, or obstructed flow of urine. Diagnostic measures may include barium x-ray studies, angiography, or tomography. Embryonal rhabdomyosarcoma occurs in the head, neck, or trunk of young children; alveolar rhabdomyosarcoma is usually seen in the extremities of adolescents; and the pleomorphic form is most common in the legs of adults. Surgical excision is rarely possible because the tumor is poorly encapsulated and tends to spread. Amputation of an affected limb or extremity may be curative. Radiotherapy and chemotherapy with combinations of actinomycin D, adriamycin, cyclophosphamide, and vinCRIStine may greatly increase the length of survival. Also called rhabdomyoblastoma, rhabdosarcoma.
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Rhabdomyosarcoma

rhab·do·my·o·sar·co·ma

(rab'dō-mī'ō-sahr-kō'mă)
A malignant neoplasm derived from skeletal (striated) muscle, classified as embryonal alveolar (composed of loose aggregates of small round cells) or pleomorphic (containing rhabdomyoblasts).
Synonym(s): rhabdosarcoma.
[rhabdo- + G. mys, muscle, + sarkōma, sarcoma]

rhabdomyosarcoma

A rare and often highly malignant tumour of muscle affecting people at both extremes of life. Treatment is by surgical removal, RADIOTHERAPY and anticancer drugs.

rhab·do·my·o·sar·co·ma

, rhabdosarcoma (rab'dō-mī'ō-sahr-kō'mă, rabdō-sahr-)
Malignant neoplasm derived from skeletal (striated) muscle, occurring in children or, less commonly, in adults.
[rhabdo- + G. mys, muscle, + sarkōma, sarcoma]

rhabdomyosarcoma (rab´dōmīō-särkō´mə),

n a malignant tumor of striated, or voluntary, muscle.
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Rhabdomyosarcoma.
Rhabdoviridae
n one of the major ribonucleic acid virus families, to which the rabies virus belongs. Viruses have a single-stranded, nonsegmented, linear molecular structure with helical symmetry.

rhabdomyosarcoma

a highly malignant tumor arising in striated muscle or in embryonal mesenchymal cells, and exhibiting differentiation along rhabdomyoblastic lines, including but not limited to the presence of cells with recognizable cross striations.
References in periodicals archive ?
The severity of rhabdomyosarcoma depends on various factors, including where in the body it developed.
A: Histologically, rhabdomyosarcoma composed of pleomorphic round to oval tumour cells.
Rhabdomyosarcoma of the oral cavity: report of eight cases.
Fine-needle biopsy and core-needle biopsy are safe methods of establishing a diagnosis of rhabdomyosarcoma without delay.
Only at the time of the third resection was the diagnosis of spindle cell rhabdomyosarcoma made.
Rhabdomyosarcoma is one of the most common tumors of pediatric age group (1).
Immunohistochemical evaluation revealed positivity for HHF-35, desmin and myogenin, thereby confirming the diagnosis of embryonal rhabdomyosarcoma.
2005) on the generation of rhabdomyosarcomas from "embedded weapons-grade tungsten alloy.
A mass in his stomach was type 4 rhabdomyosarcoma, a recurring cancer.