rhabdomyosarcoma /rhab·do·myo·sar·co·ma/ (mi″o-sahr-ko´mah) a highly malignant tumor of striated muscle derived from primitive mesenchymal cells.
rhabdomyosarcoma
rhabdomyosarcoma (rab´dōmīō-särkō´m
),
alveolar rhabdomyosarcoma a type having dense proliferations of small round cells among fibrous septa that form alveoli, seen mainly in adolescents and young adults.
embryonal rhabdomyosarcoma a type having alternating loosely cellular areas with myxoid stroma and densely cellular areas with spindle cells, seen mainly in infants and small children.
pleomorphic rhabdomyosarcoma a type having large cells with bizarre hyperchromatic nuclei, seen in the skeletal muscles, usually in the limbs of adults.
rhab·do·my·o·sar·co·ma (r b d -m -sär-k m )n. A malignant tumor derived from skeletal muscle, characterized in adults by poorly differentiated cells with large hyperchromatic nuclei. Also called rhabdosarcoma. |
rhabdomyosarcoma
[rab′dōmī′ō·särkō′mə] pl. rhabdomyosarcomas, rhabdomyosarcomata
Etymology: Gk, rhabdos + mys, muscle, sarx, flesh, oma
a highly malignant tumor derived from primitive striated muscle cells that occurs most frequently in the head and neck and is also found in the genitourinary tract, extremities, body wall, and retroperitoneum. In some cases the onset is associated with trauma. The initial symptoms depend on the site of tumor development and indicate local tissue or organ destruction, such as dysphagia, vaginal bleeding, hematuria, or obstructed flow of urine. Diagnostic measures may include barium x-ray studies, angiography, or tomography. Embryonal rhabdomyosarcoma occurs in the head, neck, or trunk of young children; alveolar rhabdomyosarcoma is usually seen in the extremities of adolescents; and the pleomorphic form is most common in the legs of adults. Surgical excision is rarely possible because the tumor is poorly encapsulated and tends to spread. Amputation of an affected limb or extremity may be curative. Radiotherapy and chemotherapy with combinations of actinomycin D, adriamycin, cyclophosphamide, and vinCRIStine may greatly increase the length of survival. Also called rhabdomyoblastoma, rhabdosarcoma.
rhabdomyosarcoma (rab´dōmīō-särkō´m
),n a malignant tumor of striated, or voluntary, muscle.
)
Rhabdomyosarcoma.
Rhabdoviridae
n one of the major ribonucleic acid virus families, to which the rabies virus belongs. Viruses have a single-stranded, nonsegmented, linear molecular structure with helical symmetry.
rhabdomyosarcoma
a highly malignant tumor arising in striated muscle or in embryonal mesenchymal cells, and exhibiting differentiation along rhabdomyoblastic lines, including but not limited to the presence of cells with recognizable cross striations.
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