reversible inhibition

reversible inhibition

inhibition of enzyme activity in which the inhibiting molecular entity can associate and dissociate from the protein's binding site.
References in periodicals archive ?
It requires a local anesthetic and the gel is injected into the lumen and works on the same basis as Reversible Inhibition of Sperm Under Guidance (RISUG).
In the recent issue of Nature Chemistry Biology, the IMED team go on to show that it is possible to use a non-catalytic lysine residue in the PPI target, Mcl-1, to achieve covalent reversible inhibition.
The project was funded by the ministry of Health and Family Welfare and the research was coordinated by the Indian Council of Medical Research Reversible Inhibition of Sperm Under Guidance ( RISUG), now in the last leg of its trials, is slated for a restricted, monitored launch by the end of this year.
RISUG - Reversible Inhibition of Sperm Under Guidance (RISUG) involves injecting a synthetic gel into the vas deferens, the tubes through which sperm travels out of the body.
Lissner's favourite male contraceptive option is called Reversible Inhibition of Sperm Under Guidance (RISUG).
Although there was a slight tendency toward increased inhibitory effect upon preincubation with TBT, the changes did not reach significance (Figure 3), in line with reversible inhibition.
Its immunosuppressant action resides in the noncompetitive, selective and reversible inhibition of inosine monophosphate dehydrogenase, thereby suppressing the de novo synthesis of guanosine nucleotides in T and B lymphocytes.
Rapamycin causes poorly reversible inhibition of mTOR and induces p53-independent apoptosis in human rhabdomyosarcoma cells.
Since late ' 80s we have been working on a method called RISUG an acronym for Reversible Inhibition of Sperm Under Guidance," says Dr Ambwani.
The presumed mechanism of action is reversible inhibition of platelet function, Dr.

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