reversible inhibition

reversible inhibition

inhibition of enzyme activity in which the inhibiting molecular entity can associate and dissociate from the protein's binding site.
References in periodicals archive ?
Reversible inhibition of mitochondrial protein synthesis during linezolid-related hyperlactatemia.
The exact mechanism of action (MOA) of rivastigmine is unknown, but it is thought to increase ACh concentrations through reversible inhibition of AChE by hydrolysis.
The project was funded by the ministry of Health and Family Welfare and the research was coordinated by the Indian Council of Medical Research Reversible Inhibition of Sperm Under Guidance ( RISUG), now in the last leg of its trials, is slated for a restricted, monitored launch by the end of this year.
RISUG - Reversible Inhibition of Sperm Under Guidance (RISUG) involves injecting a synthetic gel into the vas deferens, the tubes through which sperm travels out of the body.
Although there was a slight tendency toward increased inhibitory effect upon preincubation with TBT, the changes did not reach significance (Figure 3), in line with reversible inhibition.
These effects include its dual mechanism of highly selective, reversible inhibition of MAO-B, and state and use-dependent blockade of sodium channels that inhibit glutamate release, implicated in causing dyskinesia.
Rapamycin causes poorly reversible inhibition of mTOR and induces p53-independent apoptosis in human rhabdomyosarcoma cells.
Since late ' 80s we have been working on a method called RISUG an acronym for Reversible Inhibition of Sperm Under Guidance," says Dr Ambwani.
The presumed mechanism of action is reversible inhibition of platelet function, Dr.
Mycophenolic acid (MPA) possesses immunosuppressive, anticancer, antibacterial, and antiviral properties [1-4] and mediates its effects by noncompetitive reversible inhibition of the enzyme inosine 5'-monophosphate dehydrogenase (IMP-DH; EC 1.

Full browser ?