reverse T3


Also found in: Acronyms.

reverse T3

3,3',5'-Triiodothyronine, rT3 Lab medicine A conversion product of T4–thyroxine, the level of which reflects the rate of peripheral conversion of thyroid hormones of T4 to T3 Normal rT3 levels 0.15-0.77 mmol/L. See Euthryoid sick syndrome.

reverse T3

3,3′,5′-tri-iodothyronine.
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Drugs such as glucocorticoids, octreatide, and dopamine (a) rT3, Reverse T3 (Triiodothyronine).
Leptin resistance causes a diminished TSH secretion, a suppressed T4 to T3 conversion, an increase in reverse T3, an increase in appetite, an increase in insulin resistance, and an inhibition of lipolysis.
Reverse T3 has been shown to be a more potent inhibitor of T4 to T3 conversion than PTU (propylthiouracil), a medication used to decrease thyroid hormone levels in hyperthyroid.
Likewise, if the reverse T3 level is elevated, then it will further inhibit the conversion of T4 to T3.
She also had borderline subclinical hypothyroidism wherein her reverse T3 was mildly elevated and her free T3 was in the barely normal range.