retrotransposon


Also found in: Dictionary, Encyclopedia, Wikipedia.
Related to retrotransposon: Transposons, Transposable element, Retrotransposition

ret·ro·pos·on

(ret'rō-pōz'on),
1. A transposition of sequences in a DNA that does not originate in the DNA but rather in an mRNA that is transcribed back into the genomic DNA by reverse transcription. Synonym(s): retrotransposon
2. A transposable element.
[retro- + L. pono, pp. positum, to place, + -on]

retrotransposon

(rĕt′rō-trăns-pō′zŏn)
n.
A transposon copied from RNA with the use of reverse transcriptase.

retrotransposon

a type of TRANSPOSABLE GENETIC ELEMENT, found in eukaryotic genomes, that utilizes RNA as an intermediate and the enzyme REVERSE TRANSCRIPTASE to transpose. Reverse transcription of the RNA transcripts of the transposon produces a DNA copy that subsequently inserts into the GENOME to effect transposition. Retrotransposons may be degenerate RETROVIRUSES.

retrotransposon, retroposon

a mobile sequence of DNA that transposes via a RNA intermediate.
References in periodicals archive ?
Retrotransposons are thought to be remnants of ancient viruses that infected early animals and inserted their genes into the genome long before humans evolved.
Characterization of a mutagenic Bl retrotransposon insertion in the jittery mouse.
Unexpectedly, the researchers found that about 10 percent of the active genes belong to a group of retrotransposons known as long terminal repeat class III.
Therefore, retrotransposons could be also considered as attractive endogenous source of genetic variation.
LINE-1 elements are retrotransposon sequences, whereas ALU elements are short interspersed nuclear elements.
Using bioinformatics to compare the standard assembly of genetic elements as outlined in the reference human genome to raw whole-genome data from 310 individuals recently made available by the 1000 Genomes Project, the team revealed 1,016 new insertions of RIPs, or retrotransposon insertion polymorphisms, thereby expanding the catalog of insertions that are present in some individuals and absent in others.
Using bioinformatics to compare the standard assembly of genetic elements, the team revealed 1,016 new insertions of RIPs, or retrotransposon insertion polymorphisms, thereby expanding the catalog of insertions that are present in some individuals and absent in others.
The lawful processes of segmental duplication and of retrotransposon insertion, responsible for the generation of new genes in now-extinct ancestors, are open to experimental analysis, are starkly molecular in nature, and are inalienably part of that physical reality that we recognize as creation.
In an effort to assess their impact on gene evolution we have developed a computational pipeline that identifies LTR retrotransposon sequences within 1,000 base pairs of annotated genes.
Arabidopsis and cotton (Gossypium) as models for studying copia-like retrotransposon evolution.
vy] is a dominant mutation that is caused by the insertion of a DNA sequence known as an intracisternal A-particle (IAP) retrotransposon in front of (i.