retrotransposon


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ret·ro·pos·on

(ret'rō-pōz'on),
1. A transposition of sequences in a DNA that does not originate in the DNA but rather in an mRNA that is transcribed back into the genomic DNA by reverse transcription. Synonym(s): retrotransposon
2. A transposable element.
[retro- + L. pono, pp. positum, to place, + -on]

retrotransposon

(rĕt′rō-trăns-pō′zŏn)
n.
A transposon copied from RNA with the use of reverse transcriptase.

retrotransposon

a type of TRANSPOSABLE GENETIC ELEMENT, found in eukaryotic genomes, that utilizes RNA as an intermediate and the enzyme REVERSE TRANSCRIPTASE to transpose. Reverse transcription of the RNA transcripts of the transposon produces a DNA copy that subsequently inserts into the GENOME to effect transposition. Retrotransposons may be degenerate RETROVIRUSES.

retrotransposon, retroposon

a mobile sequence of DNA that transposes via a RNA intermediate.
References in periodicals archive ?
Currently these genetic elements drive too much attention for using as a DNA marker system due to their structural characteristics including conserved PBS (primer binding site, initiation site for reverse transcription of retrotransposon mRNA) region and LTRs at both ends.
20) Zhang and Saier, "Transposon-Mediated Adaptive and Directed Mutations and Their Potential Evolutionary Benefits"; Cordaux and Batzer, "The Impact of Retrotransposons on Human Genome Evolution"; Farkash and Luning Prak, "DNA Damage and L1 Retrotransposition.
The development of most retrotransposon-based marker systems, such as SSAP (sequence-specific amplified polymorphism), IRAP (inter-retrotransposon amplified polymorphism) and REMAP (retrotransposon-microsatellite amplified polym- orphism), requires knowledge of the sequence of a particular part of a retrotransposon.
Genome evolution of wild barley (Hordeum spontaneum) by BARE-1 retrotransposon dynamics in response to sharp microclimatic divergence.
Transposable elements: A DNA segment that can change its position within the genome; retrotransposons are a type of transposable element.
The Non-LTR retrotransposon R2 in termites (Insecta, Isoptera): characterization and dynamics.
Kalendar R, Tanskanen J, Immonen S, Nevo E, Schulman AH (2000) Genome evolution of wild barley (Hordeum spontaneum) by BARE-1 retrotransposon dynamics in response to sharp microclimatic divergence.
13) Chung, H, Bogwitz, M R, McCart, C, Andrianopoulos, A, Ffrench-Constant, R H, Batterham, P, and Daborn, P J, 'Cis-regulatory elements in the Accord retrotransposon result in tissue-specific expression of the Drosophila melanogaster insecticide resistance gene Cyp6g1', Genetics, vol.
After many generations, thousands of copies of each retrotransposon now reside in the mammalian genome.
Agrawal G, Yamazaki M, Kobayashi M, Hirochika R, Miyao A, Hirochika H: Screening of rice viviparous mutants generated by endogenous retrotransposon Tos17 insertion tagging of a zeanthin epoxidase4 gene and a novel OsTATC gene.
BLAST searching of GenBank revealed that the novel repeat shares homology with a 3622-nucleotide LTR of retrotransposon dagul.