retrograde degeneration

ret·ro·grade de·gen·er·a·tion

retrograde cell degeneration with chromatolysis of Nissl bodies and peripheral displacement of the nucleus of the cell of origin of a nerve fiber injured or sectioned.
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It is inferred that retrograde degeneration of nerve cell is a new form of cell death in "tau disease" such as AD (Kaminska et al.
Stein has noted that progesterone appears to reduce neuronal death related to retrograde degeneration following brain injury.
Nerve conduction is interrupted and the nerve fiber undergoes retrograde degeneration (Wallerian degeneration).

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