retraction syndrome

re·trac·tion syn·drome

a retraction of the globe and pseudoptosis on attempted adduction; due to coinnervation of the horizontal recti. Sometimes there is an inability to abduct the affected eye (type 1), or adduct the affected eye (type 2), or both (type 3).
Synonym(s): Duane syndrome

Duane radial ray syndrome

An autosomal dominant condition (MIM:102490) characterised by limited external rotation of the eyes and retraction with inward rotation, and by radial-ray-type bone defects in the hands (e.g., malformed or absent thumbs, extra thumb or finger-like thumb) and forearms (e.g., absence of one or more forearm bones); it may be accompanied by renal defects.

Molecular pathology
DRRS is caused by mutations of SALL4, which encodes a zinc finger transcription factor thought to play a role in musculoskeletal embryogenesis.


Alexander, U.S. ophthalmologist, 1858-1926.
Duane syndrome - a retraction of the globe and pseudoptosis on attempted adduction. Synonym(s): retraction syndrome
References in periodicals archive ?
Amblyopia was most common in nystagmus blockage syndrome (100%) and least common in Duane retraction syndrome (16.
15) reviewed patients with Duane retraction syndrome and emphasized that the most common clinical finding was AHP.
b Type 1 Duane's retraction syndrome of the right eye
Yuksel D, de Xivry JJ, Lefevre P Binocular coordination of saccades in Duane Retraction Syndrome.
Surgical and functional outcomes in bilateral exotropic Duane's retraction syndrome.
Yuksel D, Orban de Xivry JJ, Lefevre P Review of the major findings about Duane retraction syndrome (DRS) leading to an updated form of classification Vision Res.
Vertical deviation and A pattern of type III Duane retraction syndrome.
INTRODUCTION: Retraction Syndrome, also known as Stilling-Turk-Duane Syndrome, was originally described by Alexander Duane in 1905.
As already mentioned it is more common in females and left eye is more commonly involved with hypermetropia being the most common refractive error associated, we are presenting a case of a male child with right eye Duane retraction syndrome type 1A with myopia as the refractive error.
Localization of a gene for Duane retraction syndrome to chromosome 2q31.
Review of major findings about Duane Retraction Syndrome (DRS) leading to a updated form of classification.
Duane's retraction syndrome, fibrosis of the EOMs, and Chronic Progressive External Ophthalmoplegia have neurogenic and myogenic elements.