retinol binding protein

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retinol binding protein (RBP)

A single-chain polypeptide glycoprotein secreted in fat cells and the liver. It is a member of the alpha globulin family of plasma proteins. It binds and solubilizes retinol and protects it from oxidation. RBP 4 is elevated before the development of frank diabetes and appears to indicate insulin resistance.
References in periodicals archive ?
Plasma retinol binding protein (RbP) transferrin (TRF) serum albumin (PRE) and albumin (ALB) were quantified to evaluate the level of protein metabolism.
Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes.
A low molar ratio of retinol binding protein to transthyretin indicates vitamin A deficiency during inflammation: studies in rats and a posterior analysis of vitamin A-supplemented children with measles.
2005) Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes.
Association of serum retinol binding protein 4 and insulin resistance in apparently healthy adolescents.
ATRA is the functional metabolite of retinol and is delivered to cells bound to serum retinol binding protein (RBP) in the circulation.
In renal failure vitamin A metabolism changes as retinol binding protein (RBP), the carrier for vitamin A or retinol, is no longer degraded by the kidney.
Alpha 1-microglobulin, beta 2-microglobulin and retinol binding protein in childhood febrile illness and renal disease.
Prealbumin and retinol binding protein (RBP) were quantified by an immunoturbidimetric assay using the Fara centrifugal analyser (Roche Analytical Instruments) and commercially available antiserum (Behring for RBP and Atlantic Antibodies for prealbumin).
As expected, serum TTR reductions were highly correlated with parallel changes in retinol binding protein (RBP) (r2=0.
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