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retinoid X receptor

   Also found in: Acronyms, Wikipedia 0.01 sec.
retinoid X receptor
One of 2 receptors for retinoids; RXR plays a key role in organ development, in particular of the skin. Cf Retinoic acid receptor.


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The harmful effects of the chemical on the liver and the nervous and immune systems in mammals are well known, but its powerful effects on the cellular components known as retinoid X receptors (RXRs) in a range of species are a recent discovery.
In addition, RXR[alpha] was found to be the predominant retinoid X receptor [20,21].
Usually the VDREs consist of a direct repeat of two hexanucleotides spaced by three nucleotides (DR-3), to which VDR preferentially binds as a heterodimer with the retinoid X receptor (RXR) (MacDonald et al.
 
 
 
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