retinoid


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Related to retinoid: tretinoin, Retin A

retinoid

 [ret´ĭ-noid]
1. resembling the retina.
2. retinal, retinol, or any structurally similar natural derivative or synthetic compound, with or without vitamin A activity.

ret·i·noid

(ret'i-noyd),
1. Resembling a resin; resinous.
2. Resembling the retina.
3. In plural form, term used to describe the natural forms and synthetic analogues of retinol.

retinoid

/ret·i·noid/ (ret´ĭ-noid)
1. resembling the retina.
2. retinal, retinol, or any structurally similar natural derivative or synthetic compound, with or without vitamin A activity.

retinoid

(rĕt′n-oid′)
n.
Any of various natural or synthetic derivatives of vitamin A.

retinoid

[ret′inoid]
Etymology: L, rete, net; Gk, eidos, form
1 resembling the retina.
2 pertaining to any of a group of compounds whose molecules contain 20 carbon atoms structurally related to retinal, retinol, and other substances, some of which exhibit vitamin A activity. Retinoid analogs have been used in the prevention and treatment of various skin cancers and treatment of the digestive and respiratory tracts.
3 resinlike or having a resemblance to resin.

retinoid

noun
1. Vitamin A or a vitamin A-like compound.
2. Any of a class of drugs used to manage CA and other conditions–eg, hairy leukoplakia, molluscum contagiosum. See AIDS.

Retinoid

A synthetic vitamin A derivative used in the treatment of a variety of skin disorders.
Mentioned in: Rosacea

retinoid

1. resembling the retina.
2. any derivative of retinal.
References in periodicals archive ?
Granactive Retinoid is hydroxypinacolone retinoate, a cosmetic grade ester of all-trans retinoic acid.
Retinoids are another beneficial cosmetic ingredient.
Teratogenicity is the best-known serious adverse effect, and the risk of 'retinoid embryopathy' is as high as for thalidomide; mucocutaneous side-effects include initial worsening of acne, xerosis and cheilitis, retinoid dermatitis, and staphylococcal infections of the skin; ocular complications include dry eyes that can persist indefinitely; and severe depression can occur as a rare and idiosyncratic event requiring prompt attention.
Following the recent grant of orphan drug designations in the United States for QLT091001 in the treatment of LCA and RP, the issuance of this patent brings additional value and protection to our synthetic retinoid program," said Bob Butchofsky, president and CEO of QLT.
Retinoids are inherently very unstable and cosmetic formulations often incorporate anti-oxidants to preserve the retinoid compound.
Their topics include nuclear receptors, transcription factors, and signaling cascades (including retinoid signaling, Vitamin D-regulated pathways and the effects of nutrient deprivation on the expression of growth-arrest genes), amino acids, lips and glycation (including anabolic effects of amino acids and insulin in the liver and autophagy), insulin release, signaling and insulin resistance (including pancreatic beta cells as unique fuel sensors), calcium-dependent signaling, and feeding and nutrient homeostatis.
On scars that won't go away, try an over-the-counter retinoid cream, which helps skin build collagen (look for products by Neutrogena or Roe).
The anti-neoplastic agent can be an alkylating agent, an antibiotic agent, an antimetabolic agent, a retinoid, a hormonal agent, a plant-derived agent, an anti-angiogenesis agent and a biologic agent such as monoclonal antibody and interferon.
The most common prescription medications applied to the skin are retinoid creams such as Retin-A and topical antibiotics such as erythromycin.
The transcriptional effects of the retinoids are regulated by a family of nuclear receptors, the retinoid acid receptors (RARs) and the retinoid X receptors (RXRs), whose natural ligands are all-trans retinoic acid and 9-cis retinoic acid, respectively.
Previously available only in Germany, Argentina, and Canada, tazarotene belongs to the retinoid family of topical drugs (those for use on the skin) derived from vitamin K.

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