ALDH1A1

(redirected from retinaldehyde dehydrogenase 1)

ALDH1A1

A gene on chromosome 9q21.13 that encodes a cytosolic aldehyde dehydrogenase that plays a major role in detoxifying aldehydes generated by alcohol metabolism and lipid peroxidation. The ALDH1A1 gene may be involved in regulating the metabolic responses to a high-fat diet.
References in periodicals archive ?
A key step in retinoid metabolism occurs with help from an enzyme called retinaldehyde dehydrogenase 1, or Aldh1a1.
a company harnessing breakthroughs in brown fat biology and insulin sensitization to revolutionize the treatment of metabolic disease, today announced that it has secured exclusive option rights to intellectual property for three key small molecule targets - retinaldehyde dehydrogenase 1 (Aldh1a1), thioesterase superfamily member 1 (Them1), and TRPV4.