reteplase


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Related to reteplase: Tenecteplase

reteplase

 [ret´ĕ-plās]
a recombinant form of tissue plasminogen activator; used intravenously as a thrombolytic agent in treatment of myocardial infarction.

reteplase

(rĕ-tĕ'plāz),
A fibrinolytic agent that works by stimulating production of plasmin.
See also: plasmin.

reteplase

/ret·e·plase/ (ret´ĕ-plās) a recombinant form of tissue plasminogen activator; used as a thrombolytic agent in the treatment of myocardial infarction.

reteplase

[ret′ĕ-plās]
a recombinant form of tissue plasminogen activator used intravenously as a thrombolytic agent in treatment of myocardial infarction.

PLAT

A gene on chromosome 8p12 that encodes tissue plasminogen activator, which converts inactive plasminogen to plasmin by hydrolysing a single Arg-Val bond in plasminogen, thereby playing a key role in tissue remodelling, degradation, cell migration and other cellular events. PLAT directly facilitates neuronal migration.

reteplase

Retavase Cardiology A recombinant mutant of alteplase–tPA used to treat acute MI. See Acute myocardial infarction, GUSTO V.

reteplase

A drug that dissolves blood clots. A fibrinolytic drug used in the early stages of a heart attack to try to restore patency to a coronary artery branch that has been blocked by a blood clot. A brand name is Rapilysin.
References in periodicals archive ?
This study retrospectively evaluates one institution's experience using reteplase as the thrombolytic drug alone, and with the addition of the platelet inhibiting drug reopro, in more difficult cases.
Results of the Early Reteplase Thrombolysis in Myocardial Infarction-19 (ER TIMI-19) trial, reported by Dr.
The study population involves a broad range of patients presenting with STEMI, including those treated with a range of thrombolytic regimens (streptokinase, r-t-PA, reteplase, tenecteplase), primary percutaneous coronary intervention (PCI) and those not eligible for reperfusion therapy (e.
One of the new options, half-dose reteplase plus heparin and a half dose of abciximab, an antiplatelet drug, looked especially good for younger patients and those with larger infarctions, Dr.
ExTRACT is a 21,000 patient, multi-national and indication-seeking trial, investigating the efficacy and safety of LOVENOX(R) compared to UFH in patients with heart attack (STEMI) receiving thrombolytic therapy with TNK, streptokinase, alteplase or reteplase.
Since 1987, clot-dissolving agents such as t-PA, streptokinase and reteplase have been the treatment of choice for patients presenting with a heart attack within six hours from the onset of symptoms.
This ongoing Phase III, international trial is evaluating the use of ReoPro in combination with a clot-busting drug called reteplase (RETAVASE(R)) for treating heart attack patients.