retained acid syndrome

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A condition occurring in 25% of those treated–onset 2^nd day to 3^rd wk of therapy–with all-trans-retinoic acid–eg, for acute promyelocytic leukemia Clinical Fever, dyspnea, pulmonary infiltrates, pleural effusions Treatment Corticosteroids; discontinuing all-trans-retinoic acid may be ineffective. See Acute promyelocytic leukemia.

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