restriction length polymorphism

re·stric·tion length pol·y·mor·phism

, fragment length polymorphism
the existence of allelic forms recognizable by the length of fragments that result when the nucleotide chain is treated by a specific restriction enzyme that cleaves wherever a particular sequence of nucleotides occurs. A mutation in this sequence changes cleaving and hence the number of fragments.
References in periodicals archive ?
We also analyzed the A-type gene (ATI) based on restriction length polymorphism, which is a phylogenetic tool used to differentiate and classify orthopoxviruses (13).
All of these methods, however, are time-consuming and require multiple manual steps such as restriction length polymorphism analysis, electrophoresis, and hybridization with specific oligonucleotide probes.
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