Vertex Pharmaceuticals Incorporated announced the acceptance of its applications for the use of the tezacaftor/ivacaftor combination treatment in people with cystic fibrosis (CF) ages 12 and older who have two copies of the F508del mutation or one F508del mutation and one residual function
mutation that is responsive to tezacaftor/ivacaftor by the U.
The therapy helps patients with a condition that means they carry two copies of the F508del mutation, or have one such mutation and one residual function
mutation that is responsive to tezacaftor/ivacaftor.
say, where P(x) = P(x; [alpha]) is the residual function
which is the sum of the residues of the generating function, [phi](s) to be defined below, with weights and we are to express the error term [DELTA](x; [delta]) in terms of special functions and where the prime on the summation sign means that the term corresponding to ([n.
The team directed the cut to a part of the OTC gene that, if perturbed by a small insertion or deletion, would not interfere with the residual function
of the mutant OTC gene.
NPC has emphasized that it will distribute 62 more gensets in jurisdictions of the Small Power Utilities Group (SPUG) that takes the core of its residual function
following the privatization of the bulk of its power assets.
It involves the projection of the residual function
onto the span of some appropriate set of basis functions, typically arising as eigenfunctions of a singular Sturm-Liouville problem.
In Pakistan much is left to international development agencies and private charities to finance social programmes consequently, social protection become a residual function
of the state, and not the primary responsibility towards its citizens.
For each residual function
, f, we established non-lineal systems equations; for an iteration (m):
If there is significant return of renal function or if there is a single kidney with some residual function
, renal sparing surgery might be suitable.
Patients with good residual function
seem to be less tolerant of excessive dehydration.
In a sense this curve 'explains' the variance between the measured estimates and the quartic model, and so adding this residual function
to the quartic model must vastly improve the modelling.
Two sources of errors that must be considered when estimating nPNA from UKM are the rebound effect and neglected residual function