residual disease

residual disease

Oncology Malignant cells or neoplasia that remains after any form–chemotherapy, surgery, RT–of 1º treatment
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In the trial, some patients were shown to respond to treatment, including complete remission (CR) and minimal residual disease negativity (MRD-).
Because HRS cells are not present in high numbers in CHL tumors or the blood, attempts to develop clinical assays to evaluate minimal residual disease (MRD) in CHL have not resulted in any tests that could be adopted into regular clinical practice.
Improvements of these approaches could be expected to significantly impact the ability to define complete responses to chemotherapy, potentially eliminate minimal residual disease (MRD), and provide earlier detection of disease relapse, opening an earlier window for patient treatment.
The Company's first clinical application, clonoSEQ(TM), is for monitoring Minimal Residual Disease ("MRD") in blood-based cancers.
One of the labs at the centre is currently developing a test known as deduction of minimal residual disease (MRD) for detection of cancer cells in a patient's body following treatment.
Among the topics are principles of flow cytometry, limitations, acute leukaemia, myelodysplastic syndromes and myeloproliferative neoplasms, minimal residual disease, and reactive and non-neoplastic phenomena.
Optimal cytoreduction, defined as residual disease smaller than 1 cm, was not significantly different between groups: 71% of the NACT-IDS and 58% of the primary debulking cohorts.
Panels using as many as 10 colors are coming into clinical use and may offer improved sensitivity in recognizing subtly aberrant immunophenotypes, low numbers of neoplastic cells in minimal residual disease analysis, and studies of low-cellularity samples in which only 1 or a few tubes may be analyzed.
But a new study has found that residual disease - stray cancer cells which can lead to the disease coming back - can be prevented in 98% of patients undergoing breast-conserving surgery.
But a study has found that residual disease - stray cancer cells which can lead to recurrence - can be prevented in 98 per cent of patients undergoing breast conserving surgery.
Washington, Oct 19 (ANI): A new research has revealed that removing an extra two millimetres around an area of invasive breast cancer is sufficient to minimise any residual disease in 98 per cent of patients.
19-23) It is important to recognize that even though no residual disease may be evident by MRI, surgical resection is still required due to the potential underestimation of residual disease.