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repolarization

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repolarization /re·po·lar·iza·tion/ (re-po″ler-ĭ-za´shun) the reestablishment of polarity, especially the return of cell membrane potential to resting potential after depolarization.
re·po·lar·i·za·tion (r-plr--zshn)
n.
The restoration of a polarized state across a membrane.

repolarization
[rēpō′lərīzā′shən]
Etymology: L, re + polus, pole; Gk, izein, to cause
the process by which the membrane potential of a neuron or muscle cell is restored to the cell's resting potential. In a cardiac muscle cell, the repolarization process begins after phase 0 of the action potential and is completed by the end of phase 3. It encompasses the effective and relative refractory periods and correlates with the Q-T interval on the electrocardiogram. See also cardiac action potential.

repolarization [re″po-lah-rĭza´shun]
1. the reestablishment of polarity, especially the return of a cell's membrane potential to resting potential after depolarization.
2. in cardiac physiology, the restoration of the cell to its maximal diastolic potential, represented by phase 0 to phase 3 of the action potential.

repolarization
the re-establishment of polarity, especially the return of cell membrane potential to resting potential after depolarization.


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The major findings of this study indicate that: (a) Dronedarone, unlike amiodarone, does not produce considerable repolarization lengthening in dog ventricular muscle after chronic treatment.
Although the mechanism underlying the sudden cardiac death in these patients is not yet known, "we believe that the most plausible explanation is that antipsychotic drugs increase the risk of serious ventricular arrhythmias, probably through blockade of potassium channels and prolongation of cardiac repolarization.
 
 
 
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