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MRAs such as spironolactone and eplerenone can offset the damaging effect of high aldosterone levels - which rise immediately after a heart attack augmenting the benefits of optimal standard therapy including reperfusion therapy, beta-blockers, dual antiplatelet therapy, statins and ACE inhibitors, explained Prof Beygui.
sup][1],[2],[3] Reperfusion therapy, with no or minimal delay, is optimized strategy to save both vital organs in such urgency.
However, 5% of diagnosed non ST-segment myocardial infarction are posterior MI, where reperfusion therapy would be justified if the posterior leads were used [10].
An initial aspirin dose of 150-500 mg and clopidogrel dose of 75 mg/day are recommended in patients for whom no reperfusion therapy is planned (2).
6 Venous blood samples were obtained at the beginning of reperfusion (hour zero) and after reperfusion therapy at 6, 12, 24, 48, and 72 hours.
Acute ST-segment elevation myocardial infarction (STEMI) is the most dramatic manifestation of CAD with high morbidity and mortality and timely reperfusion therapy has undoubtedly proved to reduce these adverse events4.
The optimal management of STEMI patients includes providing the fastest, safest, most effective method of reperfusion therapy available, i.
Clinical value of 12-lead electrocardiogram after successful reperfusion therapy for acute myocardial infarction.
In the multicenter trial, 116 patients with acute ST-elevation MI were randomly assigned to receive an intracoronary infusion of WJMSCs or placebo into the infarct artery at five to seven days after successful reperfusion therapy.
He then referred to the American College of Cardiology and American Heart Associaton satisfactory performance measures and mentioned giving Aspirin on arrival to every patient unless contra indicated Aspirin to all AMI patients at discharge Beta Blockers at discharge Statins at discharge ACEI or ARB for LSVD at discharge time to Fibrinolic therapy time to PCI and Reperfusion therapy smoking cessation advice or counseling besides cardiac rehabilitation referral as in patient.
One reason cited for delayed reperfusion therapy in patients with AMI and LBBB is the presence of a nondiagnostic electrocardiogram.
Acute Myocardial Infarction Study of Adenosine (AMISTAD) was the first large-scale clinical trial testing adenosine as an adjunct to reperfusion therapy.

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