reperfusion


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Related to reperfusion: reperfusion arrhythmia

reperfusion

 [re″per-fu´zhun]
restoration of blood flow to an area or part that had had temporary ischemia.

reperfusion

(rē′pər-fyo͞o′zhən)
n.
The restoration of blood flow to an organ or tissue that has had its blood supply cut off, as after a heart attack.

reperfusion

[rē′pərfyo̅o̅′zhən]
blocked arteries are opened to reestablish blood flow. It may be accomplished through thrombolytic therapy or percutaneous transluminal angioplasty.

reperfusion

(re-per-fu'zhon) [ re- + perfusion]
1. The restoration of blood flow to a part of the body deprived of adequate circulation, e.g., the heart muscle in myocardial infarction or the brain in stroke. This may be accomplished by thrombolytic agents, (e.g., streptokinase or tissue plasminogen activator), or mechanical interventions (e.g., stent placement). These interventions have improved outcomes in patients with acute coronary syndromes and in patients with stroke who come to medical attention in the first few hours of their illness.
2. The reinstitution of blood flow to tissues that have been traumatized, esp. by a long period of crushing. See: crush syndrome; rhabdomyolysis
References in periodicals archive ?
Mark Roth, PhD, and colleagues examined the effects of selenium in mouse models of ischemia reperfusion injury.
In group 4 and 5, the LAD artery was ligated for 30 minutes followed by 10 minutes or 60 minutes reperfusion respectively.
GlobalData's clinical trial report, "Ischemia Reperfusion Injury Global Clinical Trials Review, H2, 2014" provides data on the Ischemia Reperfusion Injury clinical trial scenario.
14) reported a protective role for Que, when administered during reperfusion (postconditioning), in an isolated rat heart model.
The aim of this study was to investigate the effects curcumin on inflammation and oxidative stress markers in the intestinal ischemia reperfusion (IIR) injury induced rats.
CicloMulsion is a Cremophor-free formulation of the cyclophilin inhibitor, cyclosporine, under clinical development by NeuroVive for the treatment of cardiac reperfusion injury.
Reperfusion re-invigorates production of free radicals and reactive oxygen species that attack and damage cells, exacerbating inflammation, turning loose white blood cells to attack otherwise salvageable cells and maybe even inducing potentially fatal cardiac arrhythmias.
Reperfusion damage, with the sudden return of oxygen and reversal of tissue pH changes, is inevitable during the optimal therapy of AMI by prompt percutaneous coronary intervention (PCI).
Previously, several enzymes and drugs were used to treat testicular reperfusion injury.
The animals were then returned to their cages, reperfusion period was 24 hour after surgery.
Isolated rat hearts were subjected to 30min of global ischemia, followed by 45min reperfusion.
Association between timeliness of reperfusion therapy and clinical outcomes in ST-Elevation Myocardial Infarction.