reovirus


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reovirus

 [re´o-vi″rus]
any member of a family of ether-resistant RNA viruses isolated from healthy children, children with febrile and afebrile upper respiratory disease, children with diarrhea, and many animals.

Re·o·vi·rus

(rē'ō-vī'rŭs),
A genus of viruses now currently called Orthoreovirus (family Reoviridae) that are 80 nm in diameter, with distinct double layers of capsomeres, and have vertebrates as hosts; they have been recovered from children with upper respiratory tract infections, mild fever, and sometimes diarrhea, and from children with no apparent infection; from chimpanzees with coryza; monkeys, mice; and cattle feces. There are three antigenically distinct human types related by a common complement-fixing antigen and at least 12 avian orthoreoviruses.

reovirus

/reo·vi·rus/ (re´o-vi″rus)
1. any virus belonging to the family Reoviridae.
2. any virus belonging to the genus Orthoreovirus.

reovirus

(rē′ō-vī′rəs)
n. pl. reovi·ruses
Any of a family of viruses that contain double-stranded RNA and are associated with various diseases in animals, including human respiratory and gastrointestinal infections.

reovirus

[rē′ōvī′rəs]
Etymology: respiratory enteric orphan + L, virus
any one of three ubiquitous, double-stranded ribonucleic acid viruses found in the respiratory and alimentary tracts of both healthy and sick people. Reoviruses have been implicated in some cases of upper respiratory tract disease and infantile gastroenteritis.

reovirus

A family of non-enveloped, double-stranded RNA viruses Members Orthoreovirus, orbivirus, rotavirus Disease Generally asymptomatic, ±gastroenteritis, rhinopharyngitis, ±hepatitis, encephalitis, pneumonia, Colorado tick fever. See Rotavirus.

Re·o·vi·rus

(rē'ō-vī'rŭs)
A genus of viruses recovered from children with mild fever and sometimes diarrhea, and from children with no apparent infection; a causative relationship to illness has not been proven.

Re·o·vi·rus

(rē'ō-vī'rŭs)
A genus of viruses recovered from children suffering mild fever and sometimes diarrhea but also from children with no apparent infection; a causative relationship to illness has not been proven.

reovirus (rē´ōvī´rəs),

n any one of three ubiquitous, double-stranded ribonucleic acid viruses found in the respiratory and alimentary tracts in healthy and sick people. Reoviruses have been implicated in some cases of upper respiratory tract disease and infantile gastroenteritis.

reovirus

a member of the genus Orthoreovirus.
References in periodicals archive ?
Our agreement with Pfizer represents the best and quickest way for the reovirus to be developed into a product that addresses the needs of this market.
Hardev Pandha and colleagues are scheduled to deliver a poster presentation at the EORTC-AACR-NCI Symposium entitled "Synergistic Anti-Tumour Activity of Oncolytic Reovirus and Docetaxel in a PC-3 Prostate Cancer Mouse Model" at the EORTC-AACR-NCI Symposium on Molecular Targets and Cancer Therapeutics being held in Geneva, Switzerland, from October 21-24, 2008.
The reovirus infects and kills cancer cells with an activated Ras pathway.
The poster covers preclinical work using oncolytic viruses including reovirus against mesothelioma, a rare but deadly cancer.
This patent provides the Company with additional patent protection for the use of reovirus compositions for cancers and other cellular proliferative disorders in Canada," said Mary Ann Dillahunty, Vice President of Intellectual Property for Oncolytics.
TSX: ONC, NASDAQ: ONCY) ("Oncolytics") has been granted Canadian Patent 2,415,750 entitled "Methods for Preventing Reovirus Recognition for the Treatment of Cellular Proliferative Disorders.
The microorganisms can include, amongst others, the reovirus, and modified adeno, herpes, vaccinia, p53 expressing, and vesticular stomatitis viruses.
The patent covers the reovirus for pharmaceutical use in the treatment of cellular proliferative disorders in mammals.
The investigators tested reovirus against various pediatric sarcoma cell lines in vitro and in vivo.
This patent further expands our portfolio of intellectual property specifically in the area of using recombinant reovirus for the treatment of neoplasia (cancers) and non-cancer cellular proliferative diseases such as neurofibromatosis," said Dr.
The presentation - "Evaluation of Reovirus Therapy for Spontaneously Occurring Canine Tumors" - includes the results of the previously reported canine pilot study in addition to canine tumor biopsy studies that examine the range of applicability of the virus against a range of indications.
The first abstract/poster titled "Combination therapy of reovirus and PD-1 blockade effectively established tumor control via innate and adaptive immune responses," was authored by Melcher, et al.