renal clearance


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Related to renal clearance: renal clearance test

renal clearance

n.
The volume of plasma completely cleared of a specific compound per unit time and measured as a test of kidney function.

renal clearance

Therapeutics A hypothetical calculation of plasma volume in liters of unmetabolized drug cleared through the kidneys/unit time Factors influencing RC Renal blood flow, urinary pH, tubular resorption and secretion
References in periodicals archive ?
Augmented renal clearance in the ICU: Results of a multicenter observational study of renal function in critically ill patients with normal plasma creatinine concentrations.
In mild cases of pancreatitis, elevated release of amylase into the blood and subsequent renal clearance are potentially measured by the amylase creatinine clearance ratio.
Cisplatin and other drugs that are cleared via renal excretion are dosed in elderly individuals on the basis of renal clearance function to ensure that toxic levels do not build up in blood (Dollery 1999; Legha 1990).
This assumptions is also supported by the fact that the elimination half-life and the renal clearance for each of the metabolites did not differ significantly (p < 0.
These changes may be due to a compensation mechanism to reduce the renal clearance of calcium by decreasing the glomerular filtration rates in order to reestablish serum calcium balance.
Augmented renal clearance in septic and traumatized patients with normal plasma creatinine concentrations: Identifying at-risk patients.
This reduced renal clearance of FLCs may explain the increase in serum FLCs with age seen in the cohort of Katzmann et al.
With step 2, an additional 25% reduction would be taken because of the patient's decreased renal clearance, cognitive problems, and potential drug-drug interactions.
Baclofen toxicity associated with declining renal clearance after ibuprofen.
1997) proposed that susceptibility resulted from insufficient renal clearance of toxin.
Renal clearance (C) was calculated using a standard formula (C = UV/P) using plasma creatinine and lithium levels for each period.