release reaction

release reaction

a reaction which occurs when platelets react with exposed collagen fibers due to injury of a blood vessel; the release reaction causes the release of constituents from the platelets, including histamine, fibrinogen, serotonin, adenine nucleotides and other substances.
References in periodicals archive ?
Preliminary Data Suggest 'Stepped-Dosing' May Ameliorate Cytokine Release Reaction
Previous studies have shown that Genasense can occasionally induce a "cytokine release reaction," characterized by spiking fever, back pain, and hypotension.
Reactions leading to death that were specific to the Genasense treatment group included single episodes of renal failure, "cytokine release reaction," and tumor lysis syndrome.