relapsing febrile nodular nonsuppurative panniculitis
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re·lap·sing feb·rile nod·u·lar non·sup·pur·a·tive pan·nic·u·li·tis
recurrent subcutaneous nodules accompanied by fever and followed by depression of the skin on involution. The nodules show a neutrophilic lobular panniculitis with necrosis, lipid phagocytosis, and subsequent fibrosis. Most can be classified as factitious, or secondary to α1-antitrypsin deficiency, lupus profundus, pancreatic (enzymatic) fat necrosis, or cytophagic histiocytic panniculitis. Cases of undetermined cause have been called Weber-Christian disease or syndrome.