regulon


Also found in: Encyclopedia, Wikipedia.

reg·u·lon

(reg'yū-lon),
A set of structural genes, all with the same gene regulation, the gene products of which are involved in the same reaction pathway.

reg·u·lon

(reg'yū-lon)
A set of structural genes, all with the same gene regulation, with gene products involved in the same reaction pathway.

regulon

(rĕg′yoo-lŏn)
A group of unrelated genes whose transcription is either suppressed or increased by a single protein.

regulon

a system where more than one structural GENE/OPERON, each with its own PROMOTER, is under control of the same regulator molecule, for example, an activator protein or repressor protein. The genes/operons collectively forming a regulon are often non-contiguous on the genome and share common regulatory sequences, such as activator binding sites (initiators) or operators (see OPERON MODEL), each of which is recognized by the same regulator molecule. A regulon may be positively controlled by an activator protein, as in the maltose regulon of ESCHERICHIA COLI, or negatively controlled by a repressor protein, as in the arginine regulon of E.coli.
References in periodicals archive ?
Sun J, van den Heuvel J, Soucaille P, Qu Y, Zeng A-0P (2003) Comparative genomic analysis of dha regulon and related genes for anaerobic glycerol metabolism in bacteria.
Thus the uptake and subsequent damage of endothelial cells is promoted by hyphae and the expression of hyphal regulon.
coli about thirteen operons are under control of the LexA regulon, and their products are involved in several functions, such as DNA repair and induced mutagenesis.
gingivalis gene products, and upregulated 22 gene products, all of which are part of a regulon (a genetic unit) that controls availability of heme.
Cytavis Biopharma GmbH, Polaris Group, Serometrix, LLC, Regulon Inc.
Knowledge of the Fur regulon will be useful in interpreting other global analysis of transcriptional responses.
fischeri genome for other genes with putative Furbinding sites revealed 48 Fur targets that showed expression patterns similar to each other, suggesting that expression of the Fur regulon is responsive to NO in an [H-NOX.
Regulation of virulence in Vibrio cholerae: the ToxR regulon.
Subsequently he has served as Senior Vice President of Business Development at Regulon, a privately-held biotech company.
Microarray analysis identifies Salmonella genes belonging to the low-shear modeled microgravity regulon.
All isolates were phenotypically identical; they produced broad halos of hemolysis and lecithinase reactions and had positive glucose-1-phosphate acidification test results, reflecting the constitutive activation of the PrfA virulence regulon.