regulon


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reg·u·lon

(reg'yū-lon),
A set of structural genes, all with the same gene regulation, the gene products of which are involved in the same reaction pathway.

reg·u·lon

(reg'yū-lon)
A set of structural genes, all with the same gene regulation, with gene products involved in the same reaction pathway.

regulon

(rĕg′yoo-lŏn)
A group of unrelated genes whose transcription is either suppressed or increased by a single protein.

regulon

a system where more than one structural GENE/OPERON, each with its own PROMOTER, is under control of the same regulator molecule, for example, an activator protein or repressor protein. The genes/operons collectively forming a regulon are often non-contiguous on the genome and share common regulatory sequences, such as activator binding sites (initiators) or operators (see OPERON MODEL), each of which is recognized by the same regulator molecule. A regulon may be positively controlled by an activator protein, as in the maltose regulon of ESCHERICHIA COLI, or negatively controlled by a repressor protein, as in the arginine regulon of E.coli.
References in periodicals archive ?
WP2 Unravel the regulon of cesFSR and the role of cesF in cesR activity.
The whiB7 regulon also includes Rv1258c, which encodes an efflux pump, tap, that is upregulated in tandem with eis, resulting in STR resistance.
coli about thirteen operons are under control of the LexA regulon, and their products are involved in several functions, such as DNA repair and induced mutagenesis.
gingivalis gene products, and upregulated 22 gene products, all of which are part of a regulon (a genetic unit) that controls availability of heme.
Regulation of virulence in Vibrio cholerae: the ToxR regulon.
Subsequently he has served as Senior Vice President of Business Development at Regulon, a privately-held biotech company.
Microarray analysis identifies Salmonella genes belonging to the low-shear modeled microgravity regulon.
All isolates were phenotypically identical; they produced broad halos of hemolysis and lecithinase reactions and had positive glucose-1-phosphate acidification test results, reflecting the constitutive activation of the PrfA virulence regulon.
The nif genes of the nif regulon are required for production of MoFe-protein in Azotobactor vinelandii.
Hierarchical gene regulatory systems arising from fortuitous gene associations: Controlling quorum sensing by the opine regulon in Agrobacterium.
H1 2014 141 Colorectal Cancer - Pipeline by Wellstat Biologics Corporation, H1 2014 142 Colorectal Cancer - Pipeline by Regulon Inc.