regulatory site


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regulatory site

that portion of a protein, usually an enzyme, to which the product of the enzyme-substrate interaction binds and down-regulates the active site of the enzyme by altering in conformation so as to prevent further binding to the substrate. A basis for feedback regulation.
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prior to joining Genitope in December 2001, was Vice President and Regulatory Site Head with Roche Global Development, a division of F.
About 60% to 75% of mammalian gene promoters reside within CpG islands, suggesting that these regions are the key regulatory sites of gene expression.
This is possible by binding the active and regulatory sites on the receptor.
gt;> Independent data verification via search engines, regulatory sites and annual reports along with the data provided by the nominees
There are good regulatory sites, and sites that get you to an expert such as a loan broker or business attorney.
Genome Trax enables researchers to identify genome variations of functional significance by mapping them to known elements such as gene regulatory sites and disease-linked mutations.
In healthy breast epithelial cells, 14 gene regulatory sites came together to form a single, temporary transcription site, said Huang.
Therefore, the researchers also investigated how receptor complexes interact with estrogen response element (ERE) sequences, regulatory sites that turn genes off or on.
Reflecting this characteristic, it carries an apparent excess of positive regulatory sites (Wei et al.
The tool maps NGS data to known features such as HGMD([R]) disease mutations and TRANSFAC([R]) regulatory sites.
Uckun and his colleagues have discovered that the enzyme SYK kinase specifically modifies Ikaros by adding two phosphates to unique regulatory sites.
The tool maps NGS data to known features such as disease mutations and regulatory sites.