Expression of the inserted exogenous gene is then controlled by the gene regulatory sequence
of the endogenous gene (Clark et al.
In the present study for the mining of the regulatory sequence
of virulence genes of M.
For all ADH genes, researchers have identified regulatory sequence
The exact mechanism of how increased expression of Cyp6g1 occurs in DDT-resistant fruitflies is unknown at this stage, but Daborn and colleagues showed that a transposable element (sometimes known as a 'jumping gene') called Accord is inserted into the Cyp6g1 regulatory sequence
(the DNA sequences in front of a gene, controlling its expression).
The people generally possessed two to four copies of the regulatory sequence
, in contrast to just one copy for each nonhuman primate.
DcCoV UAE-HKU23 and other CoVs in betacoronavirus lineage A possess the same putative transcription regulatory sequence
motif, 5'-UCUAAAC-3', at the 3' end of the leader sequence and preceding most ORFs (Table 3; online Technical Appendix Table 1, wwwnc.
In knock-in heterozygous cells expressing hDAF on the GGTA1 locus using the gene regulatory sequence
of the GGTA1 gene, the expression of the GGTA1 gene decreased by half.
We first reported the expression of interferon alpha in the OVA(TM) System back in January, but we have now further optimized the efficiency of the process by using a modified proprietary regulatory sequence
, resulting in a 10-fold increase over previous expression levels.
spliced cyclin1 onto a regulatory sequence
of DNA, forcing cyclin1 to make its protein throughout the cell cycle instead of just before cell division.
In many cases, she says, the mutation of one regulatory sequence
of the SHOX gene is sufficient to give rise to the full-blown syndrome.
It allows us now to search for the specific regulatory sequence
In one embodiment of the invention, expression of an endogenous gene is activated or increased following integration into the cell, by non-homologous or illegitimate recombination, of a regulatory sequence
that activates expression of the gene.