A single model regressing
the SDNN index (no lag) on nickel, vanadium, and lead concentrations, adjusted for age, mean heart rate, and smoking status, was investigated.
Currently available agents are effective in prevention of the fuller development of additional lipid rich plaque, but have yet to be proved effective in regressing
or decreasing the existing plaque burden.
These findings were associated with a statistically significant increase in the rate of apoptosis in regressing
polyps showed substantial increases in the rate of apoptosis, while the rate of apoptosis in nearby normal tissue was unchanged, confirming a selective induction of apoptosis in neoplastic tissue without affecting normal cells.