hydroxylation of acyclic monoterpene alcohols by Aspergillus niger.
Now experimental and theoretical studies with wild type enzyme and an engineered mutant have shown that hydroxylation is regiospecific
at the 1-position for a family of benzocycloarene compounds: benzocyclobutene, benzocyclopentene (indian), benzocyclohexene (tetralin), and benzocycloheptene.
esterification of estrogens by lecithin:cholesterol acyltransferase.
He developed an elegant but simple method for the transformation of alcohols into halides which is much used in organic synthesis, and a very useful regiospecific
synthesis of Mannich bases.
The method is operationally simple, regiospecific
, scalable and compatible with a variety of functional groups including amines, aldehydes and heterocycles.
Purification and characterization of a regiospecific
lipase from Aspergillus terreus, Biotechnol.
Brisson C, Brassard P (1981) Regiospecific
reactions of some vinylogous ketene acetals with haloquinones and their regioselective formation by dienolization.