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The alteration of some aspect of a blockbuster drug’s formulation—e.g., purification, altered route of delivery—or the seeking of approval to market the agent for another clinical indication as a means of extending the drug’s (lucrative) patent protection
References in periodicals archive ?
Prof Jorgen Dejgaard Jensen, lead author, said: "Silent product reformulation may not achieve dramatic reductions, but there seems to be little doubt it can reduce calorie intake, and that it can do so at a relatively low cost.
As the name suggests, the 'silent' product reformulation lets the supermarket to make small changes to the recipes of their own-brand food products, without notifying the consumers explicitly.
This success builds on the retailer's wider ongoing reformulation project which has already seen a significant amount of sugar taken out of chilled juices, yogurts, soups, cordials and fizzy drinks in recent years.
These reformulations were usually semantic paraphrases and less often repetition among 10- and 14-year-olds, while they were usually explicative paraphrase (e.
Trois types de reformulations paraphrastiques qui s'apparentent a une traduction
Warner Chilcott has filed a motion to dismiss the case, essentially arguing product reformulations are per se legal.
The FDA approved 75 reformulations and 26 New Chemical Entities (NCEs) in 2009.
Data show, first, that the participants received more reformulations than error corrections, and, second, that more variation among pairs could be observed in the amount of CF received in the EC than in the REF condition: as depicted in Tables 1 and 2, the teacher-researcher provided students with 52 reformulations (M= 13) and 29 error corrections (M= 7.
A major processed food reformulation programme looks set to be a key element of the Food Standards Agency's drive to reduce fat and sugar consumption.
From the earliest days of AI, abstractions and problem reformulations and approximations have been recognized as central to AI for reasoning effectively in complex domains.
In the isolated reformulations of the cartwheeling figures in Madchen #4, 1998, we are meant to ponder cyclical motion, which is echoed in the rotation of the Ferris wheel in Huge Wheel Small Wheel, 1999, and in the repeated elliptical tracks of the cloud-home roller coaster in Wilde Maus #2, 1999.
Under these proposed reformulations of the regulations, the question of whether the CFC was the person that transformed the property would take on legal significance arguably absent under the existing regulation.