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reciprocal translocation

   Also found in: Dictionary/thesaurus, Legal, Encyclopedia, Wikipedia 0.01 sec.
translocation /trans·lo·ca·tion/ (trans″lo-ka´shun) the attachment of a fragment of one chromosome to a nonhomologous chromosome. Abbreviated t.
reciprocal translocation  the complete exchange of fragments between two broken nonhomologous chromosomes, one part of one uniting with part of the other, with no fragments left over. Abbreviated rcp.
robertsonian translocation  translocation involving two acrocentric chromosomes, which fuse at the centromere region and lose their short arms.

reciprocal translocation
n.
Translocation without demonstrable loss of genetic material.

reciprocal translocation,
the mutual exchange of genetic material between two nonhomologous chromosomes. Also called interchange. Compare balanced translocation, robertsonian translocation.

translocation [trans″lo-ka´shun]
the attachment of a fragment of one chromosome to a nonhomologous chromosome.
Translocation of a portion of one chromosome to another chromosome. Redrawn from Damjanov, 2000.
reciprocal translocation the mutual exchange of fragments between two broken chromosomes, one part of one uniting with part of the other.
robertsonian translocation that in which the breaks occur at the centromeres and entire chromosome arms are exchanged, usually involving two acrocentric chromosomes.


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As a result of reciprocal translocation, a new and abnormal protein, Bcr-Abl, causes the uncontrolled proliferation of white blood cells.
 
 
 
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