reciprocal translocation


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Related to reciprocal translocation: acrocentric chromosome, Paracentric inversion, nonhomologous chromosomes, robertsonian translocation

translocation

 [trans″lo-ka´shun]
the attachment of a fragment of one chromosome to a nonhomologous chromosome.
Translocation of a portion of one chromosome to another chromosome. Redrawn from Damjanov, 2000.
reciprocal translocation the mutual exchange of fragments between two broken chromosomes, one part of one uniting with part of the other.
robertsonian translocation that in which the breaks occur at the centromeres and entire chromosome arms are exchanged, usually involving two acrocentric chromosomes.

re·cip·ro·cal trans·lo·ca·tion

translocation without demonstrable loss of genetic material.

reciprocal translocation

the mutual exchange of genetic material between two nonhomologous chromosomes. Also called interchange. Compare balanced translocation, robertsonian translocation.

re·cip·ro·cal trans·lo·cation

(rĕ-sip'rŏ-kăl tranz'lō-kā'shŭn)
Translocation without demonstrable loss of genetic material.
References in periodicals archive ?
Meiotic outcomes in reciprocal translocation carriers ascertained in 3day human embryos.
For reciprocal translocations, the prevalence of unbalanced gametes is estimated to be between 50 and 70 per cent, thus vastly reducing the number of embryos that are available for transfer and implantation (12,13).
The reciprocal translocation involving the bcl-2 locus on chromosome 18q21 and the immunoglobulin heavy chain locus (IgH) on chromosome 14q32 is shown schematically in Fig.
Several subtypes of human acute leukemia are associated with reciprocal translocations of the Myeloid Lymphoid Leukemia (MLL) gene which fuses to more than 50 different loci.
The test cannot, for instance, detect balance rearrangements, such as balanced reciprocal translocations, balanced Robertsonian translocations, and inversions.
Single nucleotide polymorphism (SNP) microarrays (MA) may be valuable in detecting small genomic imbalances and distinguishing balanced from normal embryos for carriers of reciprocal translocations (P-65) Marie Werner Poster Session - Tuesday: Genetic Counseling