reciprocal translocation


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translocation

 [trans″lo-ka´shun]
the attachment of a fragment of one chromosome to a nonhomologous chromosome.
Translocation of a portion of one chromosome to another chromosome. Redrawn from Damjanov, 2000.
reciprocal translocation the mutual exchange of fragments between two broken chromosomes, one part of one uniting with part of the other.
robertsonian translocation that in which the breaks occur at the centromeres and entire chromosome arms are exchanged, usually involving two acrocentric chromosomes.

re·cip·ro·cal trans·lo·ca·tion

translocation without demonstrable loss of genetic material.

reciprocal translocation

the mutual exchange of genetic material between two nonhomologous chromosomes. Also called interchange. Compare balanced translocation, robertsonian translocation.

re·cip·ro·cal trans·lo·cation

(rĕ-sip'rŏ-kăl tranz'lō-kā'shŭn)
Translocation without demonstrable loss of genetic material.
References in periodicals archive ?
A few cases with reciprocal translocations and structural abnormalities of the X chromosome have been previously reported by other investigators.
Meiotic outcomes in reciprocal translocation carriers ascertained in 3day human embryos.
This report provides further information on the influence of balanced reciprocal translocations in recurrent miscarriage.
For reciprocal translocations, the prevalence of unbalanced gametes is estimated to be between 50 and 70 per cent, thus vastly reducing the number of embryos that are available for transfer and implantation (12,13).
Earlier studies (Palmer and Kilen, 1987) have resulted in the isolation of six reciprocal translocations (Table 1).
Myxoid-round cell liposarcoma is a common subtype of liposarcoma characterized by the t(12;16)(q13;p11) reciprocal translocation, which results in the formation of the FUS-DDIT3 chimeric gene (128,129) found in about 95% of myxoid and round cell liposarcoma cases (Table 3).
Reciprocal translocation t(12; 22)(q13;q13) in clear cell sarcoma of tendons and aponeuroses.
Several subtypes of human acute leukemia are associated with reciprocal translocations of the Myeloid Lymphoid Leukemia (MLL) gene which fuses to more than 50 different loci.
The test cannot, for instance, detect balance rearrangements, such as balanced reciprocal translocations, balanced Robertsonian translocations, and inversions.
Carriers of structural chromosomal rearrangements such as Robertsonian or reciprocal translocations have an increased risk of spontaneous abortion and having children with congenital anomalies.
Male infertility and chromosomal anomalies are often closely related and reciprocal translocations are the most frequent (1 in 600) structural chromosomal anomalies in humans, (14).