receptor trafficking

receptor trafficking

The movement of chemical receptors from one cellular structure to another, e.g., from the cell membrane to the cytoplasm.
References in periodicals archive ?
2012) CCL2 promotes P2X4 receptor trafficking to the cell surface of microglia.
To accomplish this function Sortilin is endowed with an ectodomain that binds a great variety of cargo proteins, and a cytosolic domain that recruits adaptor proteins to direct the receptor trafficking activities.
Subunit-specific NMDA receptor trafficking to synapses.
NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders.
Such receptor trafficking can involve movement of the receptor from synaptic to extrasynaptic regions of the cell as well as uptake of receptor molecules into the cell (Bogdanov et al.
The 1568N substitution affects receptor trafficking by disrupting a lipid-interaction/ pore-enabling motif that may also be important for membrane recycling (21,42-45).
To examine the regulation of Wnt receptor trafficking and turnover in response to Wnt signalling3.
Topics include AMPA receptor trafficking, long-term plasticity at inhibitory synapses, proteomics of the PSD, phosphorylation of site-specific antibodies, protein palmitoylation by the DHHC protein family, antibody labeling and biotinylation approaches to study neurotransmitter receptors, visualization of AMPAR trafficking and surface expression, neurotransmitter dynamics, receptors dynamics and functional tagging, RNAi and applications in neurobiology, transfecting and transducing neurons, expression of recombinant proteins in rat brains using Sindbus virus, Lentivirus-based genetic manipulation, AMPA receptor phosphorylation in synaptic plasticity, and genomic and post-genomic tools for studying synapse biology.
But we have recently found that sensitization-related facilitation of the sensorimotor synapse involves postsynaptic mechanisms, particularly modulation of AMPA receptor trafficking.
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