receptor trafficking

receptor trafficking

The movement of chemical receptors from one cellular structure to another, e.g., from the cell membrane to the cytoplasm.
References in periodicals archive ?
To accomplish this function Sortilin is endowed with an ectodomain that binds a great variety of cargo proteins, and a cytosolic domain that recruits adaptor proteins to direct the receptor trafficking activities.
Such receptor trafficking can involve movement of the receptor from synaptic to extrasynaptic regions of the cell as well as uptake of receptor molecules into the cell (Bogdanov et al.
NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders.
The 1568N substitution affects receptor trafficking by disrupting a lipid-interaction/ pore-enabling motif that may also be important for membrane recycling (21,42-45).
4 Quantitative Imaging of Receptor Trafficking (Andy R.
11 Measurement and Visualization of G-protein-coupled Receptor Trafficking by Enzyme-linked Immunosorbent Assay and Immunofluorescence (Stuart J.
To examine the regulation of Wnt receptor trafficking and turnover in response to Wnt signalling3.
Topics include AMPA receptor trafficking, long-term plasticity at inhibitory synapses, proteomics of the PSD, phosphorylation of site-specific antibodies, protein palmitoylation by the DHHC protein family, antibody labeling and biotinylation approaches to study neurotransmitter receptors, visualization of AMPAR trafficking and surface expression, neurotransmitter dynamics, receptors dynamics and functional tagging, RNAi and applications in neurobiology, transfecting and transducing neurons, expression of recombinant proteins in rat brains using Sindbus virus, Lentivirus-based genetic manipulation, AMPA receptor phosphorylation in synaptic plasticity, and genomic and post-genomic tools for studying synapse biology.
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