real prevalence

real prevalence

a technique of measuring prevalence. It is needed because of the significant errors in estimation of prevalence when the definitive test has high sensitivity but low specificity. When Se = selectivity, Sp = specificity, the real prevalence (RP) can be estimated from the apparent prevalence (AP) by the formula:
$$\hbox{RP}={\hbox{AP\ +\ S}_{\rm p}-1\over \hbox{S}_{\rm p}+ \hbox{S}_{\rm e}-1}}$$
References in periodicals archive ?
Routine colistin testing for Enterobacteriaceae would be costly and low-yield; however, without such testing, the real prevalence of mcr-1 will be underestimated.
We also recommend that studies with larger sample size may be undertaken to further evaluate the real prevalence of this parasite in our community.
Although the prevalence is likely low, especially if compared to KPC-2, the real prevalence of GES-5-producing isolates could be underestimated.
However, this may underestimate the real prevalence because American travelers who become infected during their visit to an endemic region are not included.
Users had to account for discontinuities caused by these new methods that were not related to changes in real prevalence (3).
In this connection to establish real prevalence of chronic diseases in the population according to appealability and current observation is often impossible.
Also the patients referred were representing a wider population and hence looking at the observations of our study a larger community based study will help us get the real prevalence of DR in our set up.
caninum infection, as evidenced by the presence of antibodies detected through ELISA assay, but also have a high proportion of active infections supported by parasite DNA detection in blood circulation, therefore real prevalence could be underestimated.
On the other hand, using the database of a large identification study with peer nominations (Gagne, 1998b), we found that the nonrespect of that assumption did not bias significantly the simulated data (Belanger, 1997); their fit to real prevalence measures created from the database remained very close.
Further, these results do not represent the real prevalence of RP in Puerto Rico, since the study included a limited number of patients.
Without knowing the real prevalence of hepatocellular carcinoma, the true sensitivity and specificity for AFP, US, and AFP/US in these studies cannot be determined.
The real prevalence of sustained remission may be higher than that--around 15%-20%--"because when some of the patients remit, they don't want to go back and see a psychiatrist," Dr.