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real prevalence

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real prevalence
a technique of measuring prevalence. It is needed because of the significant errors in estimation of prevalence when the definitive test has high sensitivity but low specificity. When Se = selectivity, Sp = specificity, the real prevalence (RP) can be estimated from the apparent prevalence (AP) by the formula:
$$\hbox{RP}={\hbox{AP\ +\ S}_{\rm p}-1\over \hbox{S}_{\rm p}+ \hbox{S}_{\rm e}-1}}$$


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This procedure enabled us to define the real prevalence of NoV infection and its frequent occurrence in association with another etiologic agent (18.
However, a potential selection bias is possible; because only 66% of the exposed residents filled out the questionnaire, the real prevalence of symptoms may be overestimated.
 
 
 
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