Gliosis and more reactive astrocytes
than usual were seen, some accumulating eosinophilic droplets.
Down-regulation of neurocan expression in reactive astrocytes
promotes axonal regeneration and facilitates the neurorestorative effects of bone marrow stromal cells in the ischemic rat brain.
He said that their research shows that the excessively high concentration of the GABA neurotransmitter in these reactive astrocytes
is a novel biomarker that we hope can be targeted in further research as a tool for the diagnosis and treatment of Alzheimer's disease.
At the end of all this process, astrocytes are stimulated and observation of gemistocytes which are swelled reactive astrocytes
and neuronal loss and gliosis in the striatal region in acute and chornic injuries in autopsy studies is explained in this way (9,11).
could be observed in small developing metastasis as early as 7 days following tumor cell injection (Fig.
Studying the neuronal circuitry in brain slices from the mice, the study team found that changes in reactive astrocytes
profoundly reduced the inhibitory control over brain signals.
Glial fibrillary acidic protein immunostains highlight the often evenly spaced reactive astrocytes
and their processes.
Moreover, we noted that reactive astrocytes
produced an extensive proliferation of fibrous processes and that the microglia assumed a phagocytic role.
These lesions may reveal hypercellularity and the presence of atypical reactive astrocytes
with mitotic figures, which may be observed in these demyelinating lesions and be mistaken for an astrocytic neoplasm.
Kalderon speculates that the X rays destroy cells called reactive astrocytes
, which may contribute to scarring at the site of a spinal cord injury and to the eventual degenerative response.
MAO-B activity is greatly upregulated in reactive astrocytes
surrounding amyloid plaques in the brain of AD patients in comparison to age-matched controls.
In particular, we focused on the presence and distribution of both intracellular and extracellular A[Beta] protein, NFTs, activated microglia, and reactive astrocytes
in the hippocampus and cerebral cortex.