rate-limiting


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rate-limiting

Of a delay at any stage in a metabolic pathway that restricts the speed of the whole process. The delay point might be an enzyme that is more easily saturated with substrate than any other.
References in periodicals archive ?
Glycogen synthase kinase (GSK3) regulates glycogen synthase, the rate-limiting enzyme in glycogen synthesis.
This lack of screens and assays is the rate-limiting factor that is slowing down the removal of endocrine disruptors from the environment," Colborn says.
As the pharmaceutical industry comes under increasing pressure to develop drugs faster and more efficiently, one of the crucial rate-limiting steps is the conversion of HTS 'hits' into lead compounds for preclinical evaluation.
The new TigerAccess SMC7824M/ESW is a best-in-class Edge switch, offering full L2/L4 management features that include rate-limiting, advanced QoS, Spanning Tree and Multicast.
Flexible Layer 2/3/4 traffic prioritization and rate-limiting enable Quality of Service across the network, and network segmentation is provided by port and tag-based VLANs.
Renin inhibitors, which block the initial, rate-limiting step of the rennin angiotensinaldosterone system (RAAS), are a novel approach to hypertension treatment.
1x for secure network access enabled by RADIUS for secure management; flexible traffic prioritization and rate-limiting enable advanced Quality of Service across the network with rate limiting and network segmentation via VLANs.

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