rapidly progressive glomerulonephritis

rapidly progressive glomerulonephritis

Crescentic glomerulonephritis, membranous glomerulonephritis, necrotizing glomerulonephritis Nephrology A type of kidney disease characterized by a rapid loss of renal function, with crescent-shaped deposits in at least 75% of glomeruli seen on kidney biopsies Clinical Acute nephritic syndrome or unexplained renal failure with progression to ESRD; RPGN occurs in ±1/10,000 people, especially between age 40 and 60 Associated diseases Vasculitis, polyarteritis, abscess of internal organ(s), collagen vascular disease–eg, SLE, Henoch-Schönlein purpura, Goodpasture syndrome, IgA nephropathy, membranoproliferative GN, anti-glomerular basement membrane antibody disease, Hx of malignancy or blood or lymphatic disorders, and exposure to hydrocarbon solvents. See End-stage renal disease, Glomerulonephritis.