raphe nuclei


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Related to raphe nuclei: Tuberomammillary nucleus, nucleus basalis of Meynert

ra·phe nu·cle·i

[TA]
collective term denoting a variety of nerve cell groups in and along the median plane of the medulla oblongata [nucleus raphes obscurus [TA] (obscure raphe nucleus [TA]), nucleus raphes pallidus [TA] (pallidal raphe nucleus [TA]), and caudal portions of the nucleus raphes magnus [TA] (magnus raphe nucleus [TA])]; of the pons [rostral portions of the nucleus raphes magnus [TA] (magnus raphe nucleus [TA]), nucleus raphes pontis [TA] (pontine raphe nucleus [TA]), nucleus raphes medianus [TA] (median raphe nucleus [TA] or superior central nucleus [TAalt]), and caudal portions of the nucleus raphes posterior [TA] (posterior raphe nucleus [TA]) or dorsal raphe nucleus [TAalt])]; and of the mesencephalon [rostral portions of the nucleus raphe posterior [TA] (posterior raphe nucleus [TA]), nucleus linearis inferioris [TA] (inferior linear nucleus [TA]), nucleus linearis intermedius [TA] (intermediate linear nucleus [TA]), and nucleus linearis superior [TA] (superior linear nucleus [TA])]. These nuclei include neurons characterized by their containing the indolamine transmitter agent serotonin; their serotonin-carrying axons extend rostrally to the hypothalamus, septum, hippocampus, and cingulate gyrus and include projections to brainstem, cerebellum, and spinal cord.
Synonym(s): nuclei raphes [TA]

raphe nuclei

a subgroup of the reticular nuclei of the brainstem found in narrow longitudinal sheets along the raphae of the medulla oblongata, pons, and mesencephalon. They include many neurons that synthesize serotonin. Their ascending fibers project to parts of the limbic system, and their descending fibers project to other brainstem nuclei, the medulla oblongata, and the pons. In the group are the magnus raphe nucleus, median raphe nucleus, obscurus raphe nucleus, pallidal raphe nucleus, pontine raphe nucleus, posterior raphe nucleus, inferior linear nucleus, intermediate linear nucleus, and superior linear nucleus.

ra·phe nu·cle·i

(rā'fē nū'klē-ī) [TA]
Collective term denoting a variety of unpaired nerve cell groups in and along the median plane of the mesencephalic and rhombencephalic tegmentum: the nucleus centralis tegmenti superior, nucleus raphes dorsalis, nucleus raphes pontis, nucleus raphes magnus, nucleus raphes pallidus, and nucleus raphes obscurus. These nuclei include neurons characterized by their containing the neurotransmitter serotonin; their serotonin-carrying axons extend rostrally to the hypothalamus, septum, hippocampus, and cingulate gyrus and include projections to the brainstem, cerebellum, and spinal cord.

raphe

a seam; line of union of the halves of various symmetrical parts.

abdominal raphe
linea alba.
raphe nuclei
small group of serotenergic cells in the midline of the brainstem; may be involved in the initiation of sleep.
References in periodicals archive ?
Descending projections of the raphe nuclei are small and include projections to the locus ceruleus, while ascending connections of the raphe nuclei include the hippocampus.
From there they project into the LC and other areas such as the reticular formation and the raphe nuclei, which play a role in REM sleep.
Subsequent investigations into the neural pathways of orexinergic neurons found that they project into brainstem areas such as the locus ceruleus, raphe nuclei, and reticular formation that control various aspects of rapid eye movement (REM) sleep and wake.