randomised controlled trial

randomised controlled trial

A trial in which participants are assigned by chance to receive either an experimental or control treatment. When randomisation is done properly, the effect of a treatment(s) can be studied in groups of people who are:
(1) the same at the outset, and
(2) treated the same way, except for the intervention(s) being studied. Any differences seen in the groups at the end can be attributed to the difference in treatment alone, and not to bias or chance.
References in periodicals archive ?
Randomised controlled trial of laparoscopic versus open mesh repair for inguinal hernia: outcome and cost.
In addition, the authors' conclusions regarding enteral feeding, although attractive on a physiological basis and perhaps correct, remain unproven in the absence of high-quality, level one, randomised controlled trial evidence.
Reducing SFA consumption is recommended to reduce CHD, but there is little strong randomised controlled trial (RCT) evidence of CHD events and few guidelines for specific SFA substitutes.
Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): a randomised controlled trial.
Terblanche and colleagues investigated the use of adjunctive corticosteroid treatment of clinical PCP in infants in a randomised controlled trial.
A new randomised controlled trial of the effectiveness of an intensive exercise program immediately after hospital has recently been published (Bulthuis 2007), and new studies examining the cost effectiveness of such programs should be done.
Partner notification of chlamydia infection in primary care: randomised controlled trial and analysis of resource use.
Effect of handwashing on child health: a randomised controlled trial.
Effectiveness of ototopical antibiotics for chronic suppurative otitis media in Aboriginal children: A community-based, multicentre, double-blind randomised controlled trial.
Randomised controlled trial of fecal occult blood screening for colorectal cancer.
Effectiveness of policy to provide breastfeeding groups (BIG) for pregnant and breastfeeding mothers in primary care: cluster randomised controlled trial.
Helicobacter pylori test and treat versus proton pump inhibitor in initial management of dyspepsia in primary care: multicentre randomised controlled trial (MRC-CUBE trial).