randomised controlled trial

(redirected from randomised controlled clinical trial)

randomised controlled trial

A trial in which participants are assigned by chance to receive either an experimental or control treatment. When randomisation is done properly, the effect of a treatment(s) can be studied in groups of people who are:
(1) the same at the outset, and
(2) treated the same way, except for the intervention(s) being studied. Any differences seen in the groups at the end can be attributed to the difference in treatment alone, and not to bias or chance.
References in periodicals archive ?
According to CDC, the most useful way to know whether ZMapp is effective is through randomised controlled clinical trial in people with a comparison between the outcome of patients who received the treatment and those who did not.
Prof Chakravarthy said: "These findings are important because this is the first randomised controlled clinical trial to document a beneficial effect through improved function and maintained macular pigment.
She said that the medical and scientific community recognises mindfulness and that randomised controlled clinical trials recognise that the programme does have a lasting effect on people with chronic illness and cancer patients.
We know of no randomised controlled clinical trials comparing innovator and therapeutically equivalent generic products in the treatment of allergic rhinitis.
The data contained in this meta-analysis are not new and are essentially consistent with the results from the combined analyses of randomised controlled clinical trials that Merck published in 2001 [Circulation 2001;104:2280] and again in 2003 [Am Heart J 2003;146:591].