randomised controlled trial

(redirected from randomised clinical trial)

randomised controlled trial

A trial in which participants are assigned by chance to receive either an experimental or control treatment. When randomisation is done properly, the effect of a treatment(s) can be studied in groups of people who are:
(1) the same at the outset, and
(2) treated the same way, except for the intervention(s) being studied. Any differences seen in the groups at the end can be attributed to the difference in treatment alone, and not to bias or chance.
References in periodicals archive ?
Improving women's experience during speculum examinations at routine gynaecological visits: randomised clinical trial.
o Lexipafant has successfully completed a Phase II placebo-controlled randomised clinical trial in patients with acute pancreatitis.
A randomised clinical trial between 1992 and 1998 at four Nairobi antenatal clinics evaluated 371 live-born singleton or first-born twin infants, whose mothers were randomly assigned to use formula or to breastfeed.
The course of the XIXth century saw the decline of this "heroic" age, under the pressure of the "therapeutic revolution": the common knowledge disappeared, a science-based pharmaceutical in dustry appeared, randomised clinical trials were needed, and patients had to trust their doctors without really understanding how new remedies were working.