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raltegravir

   Also found in: Wikipedia 0.01 sec.
raltegravir,
an antiretroviral.
indication This drug is used to treat HIV in combination with other retrovirals.
contraindications Breastfeeding and known hypersensitivity to this drug prohibit its use.
adverse effects Adverse effects of this drug include fatigue, fever, dizziness, nausea, vomiting, diarrhea, abdominal pain, asthenia, gastritis, rash, urticaria, pruritus, pain or phlebitis at IV site, unusual sweating, alopecia, hyperamylasia, hyperglycemia, and myopathy. Life-threatening side effects include hepatitis, oliguria, proteinuria, hematuria, glomerulonephritis, acute renal failure, renal tubular necrosis, anemia, neutropenia, and rhabdomyolysis.


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A research article published in the journal The Lancet reveals that the scientists found that an HIV integrase inhibitor called Raltegravir is overall as effective as widely used efavirenz, a reverse transcriptase inhibitor.
It is important for patients at any stage of HIV to have treatment options like raltegravir that are effective and have a demonstrated tolerability profile in order to help them manage their disease.
The first approved integrase inhibitor, raltegravir, has been associated with mild transaminase elevations but no severe hepatotoxicity has been described so far [52].
 
 
 
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